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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Administrative data

Endpoint:
bioaccumulation: aquatic / sediment
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Accepted model for calculation bioaccumulation results.

Data source

Referenceopen allclose all

Reference Type:
other: Model Results
Title:
Unnamed
Year:
2010
Report date:
2010
Reference Type:
publication
Title:
European Uniion Risk Assessment Report: Phenol
Author:
ECB
Year:
2006
Bibliographic source:
ECB
Report date:
2006

Materials and methods

Principles of method if other than guideline:
BCFBAF v3.0 model results.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Isodecyl diphenyl phosphite
EC Number:
247-777-4
EC Name:
Isodecyl diphenyl phosphite
Cas Number:
26544-23-0
Molecular formula:
C22H31O3P
IUPAC Name:
Phosphorous acid, isodecyl diphenyl ester

Study design

Route of exposure:
other: model results
Test type:
other: model results
Water / sediment media type:
not specified

Results and discussion

Bioaccumulation factor
Type:
BCF
Value:
606.5 L/kg
Basis:
whole body w.w.
Calculation basis:
steady state
Remarks on result:
other: Estimate using BCFBAF v. 3.0

Any other information on results incl. tables

--------------------------------- BCFBAF v3.00 --------------------------------

Log Kow (experimental): not available from database Log Kow used by BCF estimates: 2.78

Equation Used to Make BCF estimate: Log BCF = - 0.49 log Kow + 7.554 + Correction

Correction(s): Value No Applicable Correction Factors

Applicant's summary and conclusion

Conclusions:
regression-based method.
Executive summary:

BCF values vary from 88.29 L/kg (based on Arnot-Gobas method) to 1686 L/kg based on the BCFBAF v3.00 regression-based method. These estimates do not consider hydrolysis or biotranformation of the substance, both of which are expected to be high. Actual testing of this substance for BCF is not feasible given the rapid hydrolysis and very low water solubility. The BCF of phenol (the primary hydrolysis product) is 17.5 L/Kg (EU Phenol RAR 2006) and the BCF of isodecanol is 131 L/kg (EPISuite 4.0).