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Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
November 26 - November 28, 2019
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
GLP compliance:
no
Type of method:
effusion method: Knudsen cell
Key result
Temp.:
20 °C
Vapour pressure:
0 Pa
Key result
Temp.:
25 °C
Vapour pressure:
0 Pa
Key result
Temp.:
50 °C
Vapour pressure:
0.002 Pa

The vapour pressure was measured in the temperature range of 20 °C to 120 °C. The measured vapour pressures at the corresponding temperatures are listed in the table. After the measurement the test item remained visually unchanged. No mass loss occurred.

 

Table 1: Measured vapour pressures and corresponding temperatures

Temperature /°C

Vapour pressure / hPa

20

< 1.5E-5*

50

3.8E-5

70

1.5E-4

80

4.7E-4

90

1.6E-3

100

4.8E-3

110

1.3E-2

120

3.1E-2

100

n.e.

* below the detection limit of 1E-5 hPa

 

The data point measured at 20 °C was not included in the linear regression because it was below the detection limit. The data point at 100 °C (decreasing temperature) was not evaluable as the test cell was empty.

 

 

For an extrapolation to lower temperatures the Antoine equation was used. This is a conservative estimation of the vapour pressure of the test item for the listed temperatures. In order to further ensure a conservative approach the vapour pressures were rounded up to the next order of magnitude in order to obtain final upper limit values for the vapour pressure.

 

Table2 : Final vapour pressures

T/°C

p/hPa

p/Pa

20

4.3E-7

4.3E-5

25

8.8E-7

8.8E-5

50

2.4E-5

2.4E-3

 

 

Conclusions:
The vapour pressure of the test item was determined to be 4.3E-5 Pa (20 °C),8.8E-5 Pa (25 °C) and 2.4E-3 Pa (50 °C).
Executive summary:

A study was performed according to OECD TG 104 and Commission Regulation (EC) No. 440/2008, method A.4 in order to determine the vapour pressure of the test item by using the effusion method. The vapour pressure was measured by determining the boiling point of the test item at various temperatures between about 20 and 120°C. The vapour pressures of the test item at 20, 25 and 50 °C were extrapolated by using the Antoine constants with following results: 4.3E-5 Pa (20 °C), 8.8E-5 Pa (25 °C) and 2.4E-3 Pa (50 °C).

Description of key information

The vapour pressure of the test item was determined to be 4.3E-5 Pa (20 °C), 8.8E-5 Pa (25 °C) and 2.4E-3 Pa (50 °C) using the effusion method.

Key value for chemical safety assessment

Vapour pressure:
0 Pa
at the temperature of:
25 °C

Additional information

A study was performed according to OECD TG 104 and Commission Regulation (EC) No. 440/2008, method A.4 in order to determine the vapour pressure of the test item by using the effusion method. The vapour pressure was measured by determining the boiling point of the test item at various temperatures between about 20 and 120°C. The vapour pressures of the test item at 20, 25 and 50 °C were extrapolated by using the Antoine constants with following results: 4.3E-5 Pa (20 °C), 8.8E-5 Pa (25 °C) and 2.4E-3 Pa (50 °C).