Reaction products of 4-Diazo-3,4-dihydro-7-nitro-3-oxo-1-naphthalenesulfonic acid coupled with 7-Amino-4-hydroxy-2-naphthalenesulfonic acid, subsequently chelated with Chromium(3+) and cobalt(3+), further mixed with reaction products of 2,4,6-Trichloro-1,3,5-triazine and Ethanol, 2-[(4-aminophenyl)sulfonyl]-, 1-(hydrogen sulfate), sodium salts

Partition coefficient

Link to relevant study record(s)

Reference

Endpoint:

partition coefficient

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From 15 October, 2019 to 23 October, 2019

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study with acceptable restrictions

Qualifier:

according to guideline

Guideline:

OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)

Qualifier:

according to guideline

Guideline:

EU Method A.8 (Partition Coefficient - Shake Flask Method)

Type of method:

flask method

Partition coefficient type:

octanol-water

Key result

Type:

log Pow

Partition coefficient:

<= -4.15

Temp.:

25 °C

pH:

6

Type:

Pow

Partition coefficient:

<= 0

Temp.:

25 °C

pH:

6

Table 1. Results of the main study - n-octanol solubility of Everzol SR98

Stirring time (hours)		Cn-octanol (g/l)		Mean (g/l)		MD%		pH		Temperature (°C)
24		3.05×10^-2		3.18×10^-2		8.7		6.0		25.0 ± 0.5
48		3.16×10^-2
72		3.32×10^-2

Table 2. Summary

Sample Name	Cn-octanol(g/l)	Cwater(g/l)*	Pow= Cn-octanol/ Cwater	log Pow
Everzol SR98	3.18×10^-2	444	≤ 7.16×10^-5	≤ -4.15

*The data from EVERLIGHT Project 191014-01

Conclusions:

According to OECD 107 and EU Method A.8, the log Pow of Everzol SR98 was ≤ -4.15.

Executive summary:

This test using the procedures outlined in the EVERLIGHT Study Plan for 191009-14, OECD 107 and EU Method A.8. The water solubility of Everzol SR98 was 444 g/l and a solubility of Everzol SR98 in octanol was ≤ 3.18×10^-2g/l. The P_ow, calculated as the quotient of the octanol and water solubility, is ≤ 7.16 × 10^-5. Therefore, the log P_ow of Everzol SR98 was ≤ -4.15.

Description of key information

The log P_ow of Everzol SR98 was < -4.15 (OECD TG107 and EU Method A.8).

Key value for chemical safety assessment

Log Kow (Log Pow):

-4.15

Additional information

The maximum difference (MD) of the concentrations determined in the 24, 48 and 72 hour test sample was < 15%. The water solubility of Everzol SR98 was 444 g/l and a solubility of Everzol SR98 in octanol was ≤ 3.18×10^-2g/l. The P_ow, calculated as the quotient of the octanol and water solubility, is ≤ 7.16 × 10^-5. Therefore, the log P_ow of Everzol SR98 was ≤ -4.15.