Registration Dossier
Registration Dossier
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EC number: 949-820-9 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Long-term toxicity to fish
Administrative data
- Endpoint:
- fish early-life stage toxicity
- Data waiving:
- exposure considerations
- Justification for data waiving:
- other:
Cross-referenceopen allclose all
- Reason / purpose for cross-reference:
- data waiving: supporting information
Reference
- Registration/ Notification status for the use:
- use registered according to REACH Article 10; total tonnage manufactured/imported >=10tonnes/year per registrant
- Use name:
- Use as intermediate in the manufacture of other substances (squalane)
- Name of activity / technique:
- Use as intermediate in the manufacture of other substances (squalane)
- Environmental release category (ERC):
- ERC6a: Use of intermediate
- Name of activity / technique:
- Closed process without likelihood of exposure
- Process category (PROC):
- PROC 1: Chemical production or refinery in closed process without likelihood of exposure or processes with equivalent containment conditions
- Name of activity / technique:
- Closed continuous process with occasional controlled exposure
- Process category (PROC):
- PROC 2: Chemical production or refinery in closed continuous process with occasional controlled exposure or processes with equivalent containment conditions
- Name of activity / technique:
- Closed batch process with occasional controlled exposure
- Process category (PROC):
- PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
- Name of activity / technique:
- Transfer of the substance at dedicated facilities
- Process category (PROC):
- PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
- Name of activity / technique:
- Transfer of substance or mixture into small containers
- Process category (PROC):
- PROC 9: Transfer of substance or mixture into small containers (dedicated filling line, including weighing)
- Name of activity / technique:
- Laboratory analysis of samples
- Process category (PROC):
- PROC 15: Use as laboratory reagent
- Substance supplied to that use in form of:
- as such
- Subsequent service life relevant for this use:
- no
- Related assessment:
- use assessed in an own CSR
- Linked contributing activity:
- 01710c11-e21d-4639-bd3b-cb21416ab2c9
- Biological Sewage Treatment Plant (STP):
- no
- Particular considerations on the waste treatment operations:
- no
- Receiving surface water flow rate (m³/day):
- 18 000
- Other conditions of use impacting on environmental exposure:
- Discharge rate of effluent: >= 2E3 m3/day
- Release from the site to::
- surface water
- Release estimation method:
- estimated release factor
- Remarks:
- Industry-specific
- Release factor from the site after on-site risk management (%):
- 0
- Release from the site to::
- ambient air
- Release estimation method:
- estimated release factor
- Remarks:
- Industry-specific
- Release factor from the site after on-site risk management (%):
- 0
- Release from the site to::
- non-agricultural soil
- Release estimation method:
- estimated release factor
- Remarks:
- Industry-specific
- Release factor from the site after on-site risk management (%):
- 0
- Release factor to external waste (%):
- 0
- Exposed compartment:
- freshwater
- Clocal:
- 0 mg/L
- Predicted exposure concentration:
- 0 mg/L
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Version of exposure estimation tool:
- 2.1.2
- Exposed compartment:
- sediment (freshwater)
- Predicted exposure concentration:
- 0 mg/kg dw
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Version of exposure estimation tool:
- 2.1.2
- Exposed compartment:
- marine water
- Clocal:
- 0 mg/L
- Predicted exposure concentration:
- 0 mg/L
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Version of exposure estimation tool:
- 2.1.2
- Exposed compartment:
- sediment (marine water)
- Predicted exposure concentration:
- 0 mg/kg dw
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Version of exposure estimation tool:
- 2.1.2
- Exposed compartment:
- sewage treatment plant
- Predicted exposure concentration:
- 0 mg/L
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Version of exposure estimation tool:
- 2.1.2
- Exposed compartment:
- air
- Clocal:
- 0 mg/m³
- Predicted exposure concentration:
- 0 mg/m³
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Version of exposure estimation tool:
- 2.1.2
- Exposed compartment:
- agricultural soil
- Clocal:
- 0 mg/kg dw
- Predicted exposure concentration:
- 0 mg/kg dw
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Version of exposure estimation tool:
- 2.1.2
- Exposed compartment:
- predators' prey (freshwater)
- Predicted exposure concentration:
- 0 mg/kg ww
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Version of exposure estimation tool:
- 2.1.2
- Exposed compartment:
- predators' prey (marine water)
- Predicted exposure concentration:
- 0 mg/kg ww
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Version of exposure estimation tool:
- 2.1.2
- Exposed compartment:
- top predators' prey (marine water)
- Predicted exposure concentration:
- 0 mg/kg ww
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Version of exposure estimation tool:
- 2.1.2
- Exposed compartment:
- predators' prey (terrestrial)
- Predicted exposure concentration:
- 0 mg/kg ww
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Version of exposure estimation tool:
- 2.1.2
- Daily intake via food consumption:
- 0 mg/kg bw/day
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Version of exposure estimation tool:
- 2.1.2
- Linked contributing activity:
- c55aa072-b928-4f08-956e-be488769fc85
- Percentage (w/w) of substance in mixture/article:
- 100
- Physical form of the used product:
- liquid, including paste/slurry/suspension
- Duration of activity (hour/day):
- 8
- Technical and organisational conditions and measures:
- General ventilation: Basic general ventilation (1-3 air changes per hour)
- Effectiveness (%):
- 0
- Route affected:
- inhalation
- Technical and organisational conditions and measures:
- Occupational Health and Safety Management System: Advanced
- Technical and organisational conditions and measures:
- Local exhaust ventilation: No
- Effectiveness (%):
- 0
- Route affected:
- inhalation
- Effectiveness (%):
- 0
- Route affected:
- dermal
- Personal protection equipment:
- Respiratory protection: No
- Effectiveness (%):
- 0
- Route affected:
- inhalation
- Personal protection equipment:
- Dermal protection: No
- Effectiveness (%):
- 0
- Route affected:
- dermal
- Place of use:
- indoor
- Operating temperature (°C):
- 40
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimate:
- 0.208 mg/m³
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers
- Version of exposure estimation tool:
- 3.0
- Type of exposure:
- inhalation (external) short-term exposure
- Exposure estimate:
- 0.208 mg/m³
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers
- Version of exposure estimation tool:
- 3.0
- Type of exposure:
- dermal (external) long-term exposure
- Exposure estimate:
- 0.034 mg/kg bw/day
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers
- Version of exposure estimation tool:
- 3.0
- Linked contributing activity:
- 62f9ad30-937e-46a0-939f-d99b683975da
- Percentage (w/w) of substance in mixture/article:
- 100
- Physical form of the used product:
- liquid, including paste/slurry/suspension
- Duration of activity (hour/day):
- 8
- Technical and organisational conditions and measures:
- General ventilation: Basic general ventilation (1-3 air changes per hour)
- Effectiveness (%):
- 0
- Route affected:
- inhalation
- Technical and organisational conditions and measures:
- Occupational Health and Safety Management System: Advanced
- Technical and organisational conditions and measures:
- Local exhaust ventilation: No
- Effectiveness (%):
- 0
- Route affected:
- inhalation
- Effectiveness (%):
- 0
- Route affected:
- dermal
- Personal protection equipment:
- Respiratory protection: No
- Effectiveness (%):
- 0
- Route affected:
- inhalation
- Personal protection equipment:
- Dermal protection: No
- Effectiveness (%):
- 0
- Route affected:
- dermal
- Place of use:
- indoor
- Operating temperature (°C):
- 40
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimate:
- 2.083 mg/m³
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers
- Version of exposure estimation tool:
- 3.0
- Type of exposure:
- inhalation (external) short-term exposure
- Exposure estimate:
- 2.083 mg/m³
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers
- Version of exposure estimation tool:
- 3.0
- Type of exposure:
- dermal (external) long-term exposure
- Exposure estimate:
- 1.37 mg/kg bw/day
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers
- Version of exposure estimation tool:
- 3.0
- Linked contributing activity:
- 49b22a54-be7e-4a72-b57e-5d7425954ccf
- Percentage (w/w) of substance in mixture/article:
- 100
- Physical form of the used product:
- liquid, including paste/slurry/suspension
- Duration of activity (hour/day):
- 8
- Technical and organisational conditions and measures:
- General ventilation: Basic general ventilation (1-3 air changes per hour)
- Effectiveness (%):
- 0
- Route affected:
- inhalation
- Technical and organisational conditions and measures:
- Occupational Health and Safety Management System: Advanced
- Technical and organisational conditions and measures:
- Local exhaust ventilation: No
- Effectiveness (%):
- 0
- Route affected:
- inhalation
- Effectiveness (%):
- 0
- Route affected:
- dermal
- Personal protection equipment:
- Respiratory protection: No
- Effectiveness (%):
- 0
- Route affected:
- inhalation
- Personal protection equipment:
- Dermal protection: No
- Effectiveness (%):
- 0
- Route affected:
- dermal
- Place of use:
- indoor
- Operating temperature (°C):
- 40
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimate:
- 2.083 mg/m³
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers
- Version of exposure estimation tool:
- 3.0
- Type of exposure:
- inhalation (external) short-term exposure
- Exposure estimate:
- 2.083 mg/m³
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers
- Version of exposure estimation tool:
- 3.0
- Type of exposure:
- dermal (external) long-term exposure
- Exposure estimate:
- 0.69 mg/kg bw/day
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers
- Version of exposure estimation tool:
- 3.0
- Linked contributing activity:
- 6e475610-dca6-41de-85d4-6254f819e10a
- Percentage (w/w) of substance in mixture/article:
- 100
- Physical form of the used product:
- liquid, including paste/slurry/suspension
- Duration of activity (hour/day):
- 8
- Technical and organisational conditions and measures:
- General ventilation: Basic general ventilation (1-3 air changes per hour)
- Effectiveness (%):
- 0
- Route affected:
- inhalation
- Technical and organisational conditions and measures:
- Occupational Health and Safety Management System: Advanced
- Technical and organisational conditions and measures:
- Local exhaust ventilation: No
- Effectiveness (%):
- 0
- Route affected:
- inhalation
- Effectiveness (%):
- 0
- Route affected:
- dermal
- Personal protection equipment:
- Respiratory protection: No
- Effectiveness (%):
- 0
- Route affected:
- inhalation
- Personal protection equipment:
- Dermal protection: Yes (Chemically resistant gloves conforming to EN374) and (other) appropriate dermal protection
- Effectiveness (%):
- 80
- Route affected:
- dermal
- Place of use:
- indoor
- Operating temperature (°C):
- 40
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimate:
- 2.083 mg/m³
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers
- Version of exposure estimation tool:
- 3.0
- Type of exposure:
- inhalation (external) short-term exposure
- Exposure estimate:
- 2.083 mg/m³
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers
- Version of exposure estimation tool:
- 3.0
- Type of exposure:
- dermal (external) long-term exposure
- Exposure estimate:
- 2.742 mg/kg bw/day
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers
- Version of exposure estimation tool:
- 3.0
- Linked contributing activity:
- 908f15ff-2afa-4c8b-acb9-dc02866e4583
- Percentage (w/w) of substance in mixture/article:
- 100
- Physical form of the used product:
- liquid, including paste/slurry/suspension
- Duration of activity (hour/day):
- 8
- Technical and organisational conditions and measures:
- General ventilation: Basic general ventilation (1-3 air changes per hour)
- Effectiveness (%):
- 0
- Route affected:
- inhalation
- Technical and organisational conditions and measures:
- Occupational Health and Safety Management System: Advanced
- Technical and organisational conditions and measures:
- Local exhaust ventilation: No
- Effectiveness (%):
- 0
- Route affected:
- inhalation
- Effectiveness (%):
- 0
- Route affected:
- dermal
- Personal protection equipment:
- Respiratory protection: No
- Effectiveness (%):
- 0
- Route affected:
- inhalation
- Personal protection equipment:
- Dermal protection: Yes (Chemically resistant gloves conforming to EN374) and (other) appropriate dermal protection
- Effectiveness (%):
- 80
- Route affected:
- dermal
- Place of use:
- indoor
- Operating temperature (°C):
- 40
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimate:
- 2.083 mg/m³
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers
- Version of exposure estimation tool:
- 3.0
- Type of exposure:
- inhalation (external) short-term exposure
- Exposure estimate:
- 2.083 mg/m³
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers
- Version of exposure estimation tool:
- 3.0
- Type of exposure:
- dermal (external) long-term exposure
- Exposure estimate:
- 1.372 mg/kg bw/day
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers
- Version of exposure estimation tool:
- 3.0
- Linked contributing activity:
- adbb84a9-50b8-410f-bd42-b1f3f52e980e
- Percentage (w/w) of substance in mixture/article:
- 100
- Physical form of the used product:
- liquid, including paste/slurry/suspension
- Duration of activity (hour/day):
- 8
- Technical and organisational conditions and measures:
- General ventilation: Basic general ventilation (1-3 air changes per hour)
- Effectiveness (%):
- 0
- Route affected:
- inhalation
- Technical and organisational conditions and measures:
- Occupational Health and Safety Management System: Advanced
- Technical and organisational conditions and measures:
- Local exhaust ventilation: No
- Effectiveness (%):
- 0
- Route affected:
- inhalation
- Effectiveness (%):
- 0
- Route affected:
- dermal
- Personal protection equipment:
- Respiratory protection: No
- Effectiveness (%):
- 0
- Route affected:
- inhalation
- Personal protection equipment:
- Dermal protection: Yes (Chemically resistant gloves conforming to EN374) and (other) appropriate dermal protection
- Effectiveness (%):
- 80
- Route affected:
- dermal
- Place of use:
- indoor
- Operating temperature (°C):
- 40
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimate:
- 2.083 mg/m³
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers
- Version of exposure estimation tool:
- 3.0
- Type of exposure:
- inhalation (external) short-term exposure
- Exposure estimate:
- 2.083 mg/m³
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers
- Version of exposure estimation tool:
- 3.0
- Type of exposure:
- dermal (external) long-term exposure
- Exposure estimate:
- 0.068 mg/kg bw/day
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers
- Version of exposure estimation tool:
- 3.0
- Reason / purpose for cross-reference:
- data waiving: supporting information
Reference
- Water solubility:
- 10.2 mg/L
- at the temperature of:
- 20 °C
The water solubility of the test substance, was determined using the shake flask method according to OECD Guideline 105 and EU Method A.6 (Wohr, 2019).
Data source
Materials and methods
Results and discussion
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
