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Dissociation constant

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Endpoint:
dissociation constant
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Literature data taken from the Hazardous Substances Data Bank
Qualifier:
no guideline followed
Principles of method if other than guideline:
Data taken from the Hazardous Substances Data Bank
GLP compliance:
no
Dissociating properties:
yes
No.:
#1
pKa:
10.6
Temp.:
25 °C
Endpoint:
dissociation constant
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Value reported on Hazardous Substances Data Bank
Qualifier:
no guideline followed
Principles of method if other than guideline:
Data reported in Hazardous Substances Data Bank
GLP compliance:
no
Dissociating properties:
no
pKa:
10.41
Temp.:
25 °C
pKa:
10.3
Remarks on result:
other: Temperature not reported

The study that the pKa value of 10.3 was reported in did not report the temperature at which the test was carried out.

Conclusions:
The substances is unlikely to possess dissociating properties.

Description of key information

pka (2,4 xylenol): 10.6

pka (2,5 xylenol): 10.4

Key value for chemical safety assessment

pKa at 20°C:
10.4

Additional information