Registration Dossier

Administrative data

Endpoint:
activated sludge respiration inhibition testing
Type of information:
(Q)SAR
Adequacy of study:
key study
Study period:
26.03.2019
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification

Data source

Reference
Title:
Prediction of EC50 (Activated Sludge, Respiration Inhibition Test) for copper gluconate+copper sulphate+sodium sulphate
Year:
2019
Bibliographic source:
QSAR Toolbox 3.4.0.17
Report date:
2019

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: REACH Guidance on QSAR R6

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent
Type:
Constituent
Test material form:
liquid
Remarks:
Bluish liquid
Specific details on test material used for the study:
SMILES: O=S(=O)(O{-}.[Na]{+})O{-}.[Na]{+}_O=S1(=O)O{-}.[Cu]{2+}.O{-}1_OCC{P-}(O)C{P-}(O)C{P+}(O)C{P-}(O)C(=O)O{-}.[Cu]{2+}.O{-}C(=O)C{P-}(O)C{P+}(O)C{P-}(O)C{P-}(O)CO

Results and discussion

Effect concentrations
Key result
Duration:
3 h
Dose descriptor:
EC50
Effect conc.:
1 770 mg/L
Nominal / measured:
not specified
Conc. based on:
not specified
Basis for effect:
not specified
Remarks on result:
other: QSAR predicted value

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
The value obtained for the Activated Sludge of the prediction was 1.77E+03 mg/L. EC50 (3h)