Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 214-379-7 | CAS number: 1123-85-9
Endpoint summary
Administrative data
Description of key information
The substance has been assessed in two studies with human volunteers and in none of the volunteers exposed significant skin irritation was observed. When tested for eye irritation in rabbits, redness was observed, but as only 0.625% test substance in water was applied, it is concluded that the substance as such shall be considered as an eye irritant, category 2.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Justification for classification or non-classification
The substance was investigated for skin irritation/corrosion and was found not being irritant to human skin. In a study to investigate eye-irritation/damage the scores rad in the study did not require classification for eye-irritation when compared with criteria as laid out in GHS/CLP. However, the concentration tested was only 0.625% in water and scores for redness were only slightly below the classification threshold, but fully reversible. Thus it is decided to not classify the substance for skin irritation/corrosion, but to classify the substance as an eye irritant, Category 2 according to CLP (Regulation EC No. 1272/2008).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
