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EC number: 478-900-1 | CAS number: 6156-18-9
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
The BCF for BMTP was calculated to be 29 at a concentration of 0.20 mg/L (and 0 at 0.02 mg/L). The uptake and depuration rate constants, k1 and k2, were determined to be 37 and 1 for the 0.20 mg/L test concentration. Thus BMTP would not be classified as bioaccumulative according to the PBT assessment criteria.
Key value for chemical safety assessment
- BCF (aquatic species):
- 29 dimensionless
Additional information
The bioconcentration potential of 2,2-bis(methylthio)propane (BMTP) in rainbow trout (Oncorhynchus mykiss) was evaluated according to the OECD Guidelines for Testing of Chemicals (1996) No 305 (Mead, 2012). Rainbow trout were exposed to an aqueous solution of BMTP at nominal concentrations of 0.020 and 0.20 mg/L for a period of 19 days under dynamic test conditions. Samples of test fish were taken from the solvent control, 0.020 and 0.20 mg/L test groups on days 2, 6, 9, 13 and 16 of the uptake phase and the concentration of test item in the fish tissues determined. After 19 days exposure the remaining fish were subjected to a depuration period of 11 days. Samples of test fish were taken from the solvent control, 0.020 and 0.20 mg/L test groups on days 1, 4, 8 and 10 of the depuration phase and the concentration of test item determined. The BCF for the test item in the whole fish after 16 days were calculated to be 0 at a concentration of 0.020 mg/L and 29 at a concentration of 0.20 mg/L. The BCFk after 16 days for the 0.20 mg/L test concentration was calculated to be 37. A BCFk was not calculated for the 0.020 mg/L test concentration given that the BCF was 0. The uptake and depuration rate constants, k1 and k2, were determined to be 37.3241 and 1.0000 for the 0.20 mg/L test concentration. As the test item had a log Kow of greater than 3, the BCF values were also calculated as a function of the lipid content. The values were below 2000 and thus the test item would not be classified as bioaccumulative according to the PBT assessment criteria.
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