Registration Dossier
Registration Dossier
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EC number: 701-333-0 | CAS number: -
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vitro / ex vivo
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- QSAR
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2017
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- QSAR
- GLP compliance:
- no
Test material
- Reference substance name:
- Reaction products of 2,2-dimethylpropane-1,3-diol with 1-chloro-2,3-epoxypropane
- EC Number:
- 701-333-0
- Molecular formula:
- C11H20O4
- IUPAC Name:
- Reaction products of 2,2-dimethylpropane-1,3-diol with 1-chloro-2,3-epoxypropane
- Details on test material:
- It is a UVCB substance.
1
Results and discussion
In vitro
Results
- Remarks on result:
- positive indication of irritation
- Remarks:
- QSAR
Applicant's summary and conclusion
- Interpretation of results:
- Category 2 (irritant) based on GHS criteria
- Conclusions:
- It is in the CLP Annex VI ( harmonised list) as skin irritant.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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