Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
in vitro gene mutation study in bacteria
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Reference
Reference Type:
review article or handbook
Title:
Ames-Test
Author:
Romualdo Benigni
Year:
2011
Bibliographic source:
CCRIS database,Toxnet databases, Bacterial mutagenicity ISSSTY

Materials and methods

GLP compliance:
not specified
Type of assay:
bacterial reverse mutation assay

Method

Species / strain
Species / strain / cell type:
other: TA 100 and TA 1535
Metabolic activation:
with and without
Metabolic activation system:
S9

Results and discussion

Test results
Species / strain:
other:
Metabolic activation:
with and without
Genotoxicity:
negative
Cytotoxicity / choice of top concentrations:
not specified

Applicant's summary and conclusion