Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Justification for type of information:
1. SOFTWARE

EPISuite 4.11

2. MODEL (incl. version number)

BIOWIN 4.10

3. SMILES OR OTHER IDENTIFIERS USED AS INPUT FOR THE MODEL

O(C1CCC2)C1CCC2

4. SCIENTIFIC VALIDITY OF THE (Q)SAR MODEL

See On-Line BIOWIN™ User's Guide (v4.10) in EPI Suite helpfile

5. APPLICABILITY DOMAIN

See On-Line BIOWIN™ User's Guide (v4.10) in EPI Suite helpfile. Substances with structural analogy are in the trainingset,
e.g. several epoxides and cycloalkanes, cycloalkanols and cycloalkanones.

6. ADEQUACY OF THE RESULT

The substance is used as an onsite intermediate in the synthesis of another substance. There is no widespread or consumer use.
For the onsite riskassessment the predicted value is sufficient. It is a conservative worst case approach.

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
2012

Materials and methods

Test guideline
Guideline:
other: REACH Guidance on QSARS R6 2008

Results and discussion

% Degradation
Remarks on result:
not readily biodegradable based on QSAR/QSPR prediction

Applicant's summary and conclusion