(4R,6R)-4-Hydroxy-2,2,6-trimethylcyclohexanone / 60046-50-6

Melting point / freezing point

Administrative data

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: The study was carried out in compliance with Directive 92/69/EEC, Part A.1 "Melting/Freezing Temperature", 1992, and OECD Guideline for Testing of Chemicals No. 102 "Melting point/Melting range", 1995, with no deviations reported.

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1999

Report date:

1999

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Remarks:

Swiss Federal Department of the Interior

Type of method:

capillary method

Test material

Test material information

Constituent 1

Reference substance name:

(4R,6R)-4-hydroxy-2,2,6-trimethylcyclohexan-1-one

EC Number:

700-052-0

Cas Number:

60046-50-6

Molecular formula:

C9H16O2

IUPAC Name:

(4R,6R)-4-hydroxy-2,2,6-trimethylcyclohexan-1-one

Details on test material:

- Name of test material (as cited in study report): Actinol
- Physical state: White solid
- Analytical purity: 99.5 %
- Lot/batch No.: 410016
- Expiration date of the lot/batch: 31 July 2000
- Stability under test conditions: max 5 days
- Storage condition of test material: At room temperature, protected from sunlight
- Other:

Results and discussion

Melting / freezing point

Melting / freezing pt.:

49.3 °C

Atm. press.:

1 013 hPa

Any other information on results incl. tables

Table 1: Results for the melting temperature in six single tests.

Test	Starting temperature (°C)	Heating rate (K/min)	Melting point (°C)	Melting point (K)
1^st main test	29	0.5	49.2 49.2 49.3	322.4 322.4 322.5
2^nd main test	38	0.5	49.3 49.3 49.3	322.5 322.5 322.5
Mean (st.dev.)			49.3 (0.1)	322.5 (0.1)

Applicant's summary and conclusion

Conclusions:

The testing substance Actinol has its melting point at 49.3 +/- 0.1 °C or 322.5 +/- 0.1 K.

Executive summary:

The determination of the melting point of the test substance Actinol was performed according to the EEC Directive 92/69, A.1, 1992, and the OECD Guideline No. 102, 1995.

The results of six individual tests are shown in table 1. A total of 6 samples were heated at the relevant temperature with a heating rate of 0.5 K/min. All samples were completely melted between 49.2 ° and 49.3 °C. After the measurement, the samples were melted and colourless.

In conclusion, the melting point of Actinol is 49.3 +/- 0.1 °C.