2H-Pyran, 2-[4'-[difluoro(3,4,5-trifluorophenoxy)methyl]-3',5'-difluoro[1,1'-biphenyl]-4-yl]-5-ethyltetrahydro-

Particle size distribution (Granulometry)

Link to relevant study record(s)

Reference

Endpoint:

particle size distribution (granulometry)

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2008-05-07

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions)

Deviations:

no

Principles of method if other than guideline:

The maximum diameters (fibre lengths) have been put in size classes according to the requirements of the OECD test. The minimum size of the first size class has been set to 1 μm, that deviates from the OECD requirement of 0 μm due to the reduced resolution of the light optical microscope. The minimum diameters (fibre diameters) have been put in size classes according to the requirements of the OECD test. The minimum size of the first size class has been set to 1 μm, that deviates from the OECD requirement of 0.1 μm due to the reduced resolution of the light optical microscope.

GLP compliance:

no

Type of method:

determination of fibre length and diameter distributions

Type of particle tested:

primary particle

Type of distribution:

counted distribution

Key result

Percentile:

other: length

Mean:

>= 5 - <= 10 µm

Remarks on result:

other: no SD is indicated

Key result

Percentile:

other: Diameter

Mean:

> 3 µm

Remarks on result:

other: no SD is indicated

Minimum Diameter Distribution the test item: No diameters < 3 µm were measured.

Length Distribution of the test item: The majority of particles have a length between 5 and 10 µm.

Conclusions:

Minimum Diameter Distribution of the test item: No diameters < 3 µm were measured.
Length Distribution of the test item: The majority of particles have a length between 5 and 10 µm.

Executive summary:

A study was conducted according to OECD TG 110 to determine the particle size distribution of the test item. The particle size distribution was determined the light optical microscope. The fibre length and diameter distribution was obtained by determined the maximum and minimum diameters on microscopic images of the particles observed. No diameters < 3 µm were measured (minimum diameter distribution) and the majority of the particles have a length between 5 and 10 µm (length distribution).

Description of key information

In a granulometry study no diameters < 3 µm were measured (minimum diameter distribution) and the majority of the particles have a length between 5 and 10 µm (length distribution) (reference 4.5 -1).

Additional information

A study was conducted according to OECD TG 110 to determine the particle size distribution of the test item. The particle size distribution was determined the light optical microscope. The fibre length and diameter distribution was obtained by determined the maximum and minimum diameters on microscopic images of the particles observed. No diameters < 3 µm were measured (minimum diameter distribution) and the majority of the particles have a length between 5 and 10 µm (length distribution).