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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Reference
Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
GLP compliance:
yes
Test organisms (species):
Daphnia magna
Test type:
static
Water media type:
freshwater
Limit test:
yes
Total exposure duration:
48 h
Hardness:
total hardness; 255 mg/L as CaCO3
Test temperature:
19.6-19.9ºC
pH:
pH 7.98-8.10
Dissolved oxygen:
8.77-9.07 mg/L
Nominal and measured concentrations:
Range-finding test: 1, 10, 100 mg/L (nominal conc.)
Solubility test: 100 mg/L (nominal conc.)
Stability test: 105.3-111.4%
Main test: 89.4 mg/L (meas. conc.)
Key result
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
> 89.4 mg/L
Nominal / measured:
meas. (arithm. mean)
Conc. based on:
other: by preparing Water Accomodated Fractions (WAFs)
Basis for effect:
mortality
Validity criteria fulfilled:
yes

Description of key information

Key value for chemical safety assessment

Additional information