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Physical & Chemical properties

Water solubility

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Administrative data

water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Study Experimental Work 2013-03-26 to 2013-05-31. Study report complete 2013-10-10.
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Meets the criteria for classification as reliable without restriction according to Klimisch et al (1997)

Data source

Reference Type:
study report
Report date:

Materials and methods

Test guideline
according to guideline
OECD Guideline 105 (Water Solubility)
GLP compliance:
Type of method:
flask method

Test material

Constituent 1
Chemical structure
Reference substance name:
lithium 3-((3,4-dicyanophenyl)thio)propane-1-sulfonate
EC Number:
Cas Number:
Molecular formula:
lithium 3-((3,4-dicyanophenyl)thio)propane-1-sulfonate
Test material form:
solid: particulate/powder

Results and discussion

Water solubility
Water solubility:
293.2 g/L
25 °C
Remarks on result:
other: pH 9.95-10.03
Details on results:
The standards used for the quantification of the test item in the test solutions showed satisfactory agreement through the run and between them. The % RSD of the area of the 5 injections of Standard 1A was within the 5% acceptance criteria. The % RSD of the retention time of the 5 injections of Standard 1A was also within the 1% acceptance criteria, therefore confirming the suitability of the method.

Test Concentration S193115 Bx398
mg/l % w/v
Injection 1 Injection 2 Mean pH
Test 1 292425 293750 29.31 10.03
Test 2 291225 291425 29.13 9.99
Test 3 294388 295850 29.51 9.95
Test 4 292038 293250 29.26 9.89
Test 5 291525 293263 29.24 9.84
OECD Guideline 105 states that if the concentrations measured in at least the two of the last Tests (e.g Test 2 and Test 3) do not differ by more than 15%, as it is the case in this study, the test is satisfactory.
The average result from Test 1, Test 2 and Test 3 was reported as a final result for the water solubility test:
29.3 % w/v at 25 C +/- 1 C

Applicant's summary and conclusion

Interpretation of results (migrated information): very soluble (> 10000 mg/L)
The water solubility of the test material was determined to be 293.2 g/l in this study. Therefore the test material is very soluble in water.
Executive summary:


This study was undertaken to determine the water solubility of the test material. The method used was compatible with OECD Guideline 105 (Flask Method).

Results & Conclusions

The water solubility of the test material was determined to be 293.2 g/L in this study. Therefore the test material is very soluble.