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EC number: 264-709-9 | CAS number: 64157-14-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 17 - 23 Sep 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Version / remarks:
- 1992
- GLP compliance:
- yes
Test material
- Reference substance name:
- Hydrogen tetrakis[2,2-bis[(allyloxy)methyl]butan-1-olato-O1]bis(ditridecyl phosphito -O'')titanate(2-)
- EC Number:
- 264-709-9
- EC Name:
- Hydrogen tetrakis[2,2-bis[(allyloxy)methyl]butan-1-olato-O1]bis(ditridecyl phosphito -O'')titanate(2-)
- Cas Number:
- 64157-14-8
- Molecular formula:
- not applicable (UVCB substance)
- IUPAC Name:
- dihydrogen 2-{[(di{[bis(tridecyloxy)phosphanyl]oxido}tris({2,2-bis[(prop-2-en-1-yloxy)methyl]butyl}oxido)titaniotetrakis(ylium))oxido]methyl}-1-(prop-2-en-1-yloxy)-2-[(prop-2-en-1-yloxy)methyl]butane
- Test material form:
- liquid
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): collected from the Easton Wastewater Treatment Facility, Easton, Maryland, USA on September 17, 2018. The Easton facility treats predominantly residential wastes
- Preparation of inoculum for exposure: The sludge was sieved using a 2-mm screen and adjusted to approximately 1000 mg total suspended solids/L with mineral media and then aerated at test temperature until use
- Concentration of sludge: 1000 mg total suspended solids/L - Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 5.267 mg/L
- Based on:
- DOC
- Remarks:
- mean of three replicates
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- TEST CONDITIONS
- Composition of medium:
2470 mL of high grade water
3 mL calcium chloride solution (2.75%)
3 mL of ferric chloride solution (0.025%)
3 mL of magnesium sulfate solution (2.25%)
30 mL of phosphate buffer (pH 7.4)
- Test temperature: 19.15-21.60 ºC
- pH: 7.57-7.62
- Suspended solids concentration: ≤30 mg/L
TEST SYSTEM
- Culturing apparatus: amber 4-liter bottles
- Number of culture flasks/concentration: 3
- Method used to create aerobic conditions: air entering the chambers was passed through Drierite™ to remove ambient moisture and then through Ascarite® to produce CO2-free air.
- Details of trap for CO2 and volatile organics if used: 0.5 M potassium hydroxide (KOH)
- Measuring equipment: Shimadzu Model TOC-VCSH carbon analyzer
SAMPLING
- Sampling frequency: days 3, 6, 8, 11, 15, 19, 22, 26 and 28
CONTROL AND BLANK SYSTEM
- Inoculum blank: yes, 3 replicates
- Reference control: yes, 3 replicates
- Toxicity control: yes, 1 replicate (10 mg C/L reference and test substances respectively).
Reference substance
- Reference substance:
- benzoic acid, sodium salt
Results and discussion
% Degradation
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 40.3
- Sampling time:
- 28 d
- Remarks on result:
- other: average of 3 replicates
- Details on results:
- The toxicity control achieved >25% degradation by Day 14 and therefore the test substance is considered non-inhibitory at the concentration tested in this study.
BOD5 / COD results
- Results with reference substance:
- Biodegradation rate Sodium benzoate >60% based on CO2 on day 6
Any other information on results incl. tables
Table 1: Cumulative Percent of Theoretical Carbon Dioxide Evolved
Day |
Blank control (mean of three replicates) |
Reference substance replicate 1 |
Reference substance replicate 2 |
Reference substance replicate 3 |
Mean |
Test substance replicate 1 |
Test substance replicate 2 |
Test substance replicate 3 |
mean |
Toxicity control |
3 |
NA |
35.7 |
40.4 |
42.0 |
39.37 |
0.9 |
-4.3 |
1.5 |
-0.63 |
15.0 |
6 |
NA |
64.0 |
71.2 |
67.4 |
67.53 |
2.1 |
1.6 |
3.2 |
2.30 |
29.4 |
8 |
NA |
76.6 |
81.6 |
77.8 |
78.67 |
2.5 |
4.4 |
4.3 |
3.73 |
34.8 |
11 |
NA |
84.9 |
89.4 |
85.4 |
86.57 |
4.7 |
7.6 |
4.3 |
5.53 |
41.8 |
15 |
NA |
89.4 |
93.8 |
90.5 |
91.23 |
10.5 |
14.1 |
7.7 |
10.77 |
49.9 |
19 |
NA |
91.7 |
95.7 |
92.8 |
93.40 |
20.6 |
23.6 |
13.5 |
19.23 |
55.1 |
22 |
NA |
94.1 |
97.9 |
96.4 |
96.13 |
28.7 |
30.3 |
18.9 |
25.97 |
59.6 |
26 |
NA |
94.4 |
98.8 |
99.3 |
97.50 |
35.9 |
36.1 |
27.3 |
33.10 |
63.3 |
29 |
NA |
94.1 |
99.9 |
100.8 |
98.27 |
43.7 |
43.0 |
34.3 |
40.33 |
70.7 |
Cumulative Average Day 29 (n=3) |
98.3 |
40.3 |
70.7 |
|||||||
Standard dev. |
3.6 |
5.2 |
|
Table 2: Validity criteria for OECD 301.
Criterion from the guideline |
Outcome |
Validity criterion fulfilled |
Difference of extremes of replicate values of the removal of the test chemical at the plateau, at the end of the test or at the end of the 10-d window, as appropriate, is less than 20%. |
<20% |
yes |
Percentage degradation of the reference compound reached the pass level by day 14 (≥ 60%). |
67.53 % at day 6
|
yes |
The toxicity control should degrade to at least 35% (based on DOC) or at least 25% (based on ThOD or ThCO2) within 14 d. |
49.9% at day 14 |
yes |
The IC content of the test substance suspension in the mineral medium at the beginning of the test must be less than 5% of the TC. |
n.d. |
n.d. |
The total CO2 evolution in the inoculum blank at the end of the test should not normally exceed 40 mg/L medium. |
18 mg CO2/L |
yes |
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Remarks:
- For further details please refer to “Any other information on results incl. tables”.
- Interpretation of results:
- other: not readily biodegradable according to OECD criteria
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