Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 600-872-8 | CAS number: 108419-35-8
Endpoint summary
Administrative data
Description of key information
In an acute oral toxicity study in mail and female Sprague-Dawley rats with the test substance,no deaths or adverse clinical signs were noted. There were no adverse necropsy findings. The acute oral LD 50 value was found to be greater than 5000 mg/kg bw. In an acute dermal toxicity study in mail and female New Zeland White rabbits with the test substance, no deaths were noted during the obsrvation period. During necropspsy, it revealed liver and salivary gland discoloration in 1 animal; kidney discoloration and spleen enlargement in 1 animal and alopecia in 1 animal. The acute dermal LD 50 value was found to be greater thn 3150 mg/kg bw.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 3 160 mg/kg bw
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 3 160 mg/kg bw
- Quality of whole database:
- The key result is based on the guideline study conducted in rabbits.
Additional information
Justification for classification or non-classification
This substance is not classified based on the Oral LD50 of >5000 mg/kg bw and dermal LD50 of >3160 mg/kg bw.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
