Savory, Satureja hortensis, ext.

Partition coefficient

Link to relevant study record(s)

Reference

Endpoint:

partition coefficient

Type of information:

other: literature and QSAR calculation

Adequacy of study:

weight of evidence

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Reason / purpose for cross-reference:

reference to other study

Reason / purpose for cross-reference:

reference to other study

Reason / purpose for cross-reference:

reference to other study

Reason / purpose for cross-reference:

reference to other study

Reason / purpose for cross-reference:

reference to other study

Reason / purpose for cross-reference:

reference to other study

Reason / purpose for cross-reference:

reference to other study

Reason / purpose for cross-reference:

reference to other study

Reason / purpose for cross-reference:

reference to other study

Reason / purpose for cross-reference:

reference to other study

Reason / purpose for cross-reference:

reference to other study

Principles of method if other than guideline:

No study was conducted on the Summer Savory oil itself. The test item is a natural complex substance (NCS). It is a UVCB substance having several constituents, 11 of which represent more than 95% of that mixture. The eleven known components of the UVCB substance (more than 95% of the composition) have log Pow that range between 3.49 and 6.3 (literature and QSAR calculation). Thus the log Pow of the substance is defined as the range of the log Pow of its consituents.

Partition coefficient type:

octanol-water

Key result

Type:

log Pow

Partition coefficient:

>= 3.49 - <= 6.3

Temp.:

20 °C

Remarks on result:

not measured/tested

Remarks:

applicable for essential oils.

Table 1. Known components of the summer savory oil and their log Pow values as extracted from the scientific information sources.

№	Constituent name	CAS №	log Pow
1	Carvacrol	499-75-2	3.49
2	p-mentha-1,4-diene/Gamma Terpinen	99-85-4	4.5
3	7-methyl-3-methyleneocta-1,6-diene/ Myrcene	123-35-3	4.17
4	Pin-2(3)-ene/ a-pinene	80-56-8	4.83
5	Beta-Pinene	18172-67-3	4.16
6	1-isopropenyl-4-methylbenzene/ Para-Cymene	99-87-6	4.1
7	Alpha-Terpinene	99-86-5	4.25
8	Dipentene/limonene	138-86-3	4.57
9	Alpha-Thujene	2867-05-2	4.61
10	Beta-caryophyllene	87-44-5	6.3
11	Beta-Bisabolene	495-61-4	5.2

Conclusions:

The eleven known constituents of Summer Savory oil (more than 95% of the composition) have log Pow that range between 3.49 and 6.3 (literature and QSAR calculation). Therefore, the log Pow of the substance is between 3.49 and 6.3.

Executive summary:

The eleven known constituents of Summer Savory oil (more than 95% of the composition) have log Pow that range between 3.49 and 6.3 (literature and QSAR calculation). Therefore, the log Pow of the substance is between 3.49 and 6.3. As the substance is a UVCB with constituents of different log Pow, the global log Pow of the test item will depend on the composition and the loading rate (with varying ratio of constituents in the dissolved phase). Therefore, the log Pow of the 11 major constituents of the substance are considered and no single key value was retained.

Description of key information

The eleven known components of the UVCB susbtance (more than 95% of the composition) have log Pow that range between 3.49 and 6.3 (literature and QSAR calculation).

Additional information

No study was conducted on the Summer savory oil itself. The test item is a natural complex substance (NCS). It is a UVCB substance composed of several constituents, 11 of which represent more than 95% of it.