2-hydroxy-3-propyl-2H-furan-5-one

Surface tension

Administrative data

Endpoint:

surface tension

Type of information:

experimental study

Adequacy of study:

key study

Study period:

31 July 2018 - 19 April 2019

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Cross-reference

Reason / purpose for cross-reference:

reference to other study

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

08 August 2018 - 17 October 2018

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Reason / purpose for cross-reference:

reference to other study

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Version / remarks:

2016

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Version / remarks:

1995

Deviations:

no

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7840 (Water Solubility)

Version / remarks:

1998

Deviations:

no

GLP compliance:

yes

Type of method:

flask method

Key result

Water solubility:

121 g/L

Conc. based on:

test mat.

Loading of aqueous phase:

540 g/L

Incubation duration:

>= 0 - <= 72 h

Temp.:

20 °C

pH:

2.9

Remarks on result:

other: reported value = corrected for purity

Details on results:

- The mean of the concentrations after 24, 48 and 72 h was reported as the water solubility of the substance.
- Maximum difference (24, 48 and 72 h) meets the criterion of ≤ 15% (i.e. 2.9%)

- No test item was detected in the pretreated sample from the blank.

Table: water solubility results (flask method)

Stirring time [hours]	Analyzed concentration [g/L]	Mean [g/L]	Maximum difference [%]	pH
24	120	121	2.9	2.9
48	124
72	120

reported concentrations are corrected for the purity of the test item

Conclusions:

The water solubility of the substance at 20°C was determined to be 121 g/L (based on purity correction).

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2019

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

EU Method A.5 (Surface Tension)

Version / remarks:

2016

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

OECD Guideline 115 (Surface Tension of Aqueous Solutions)

Version / remarks:

1995

Deviations:

no

GLP compliance:

yes

Type of method:

OECD harmonised ring method

Test material

Test material information

Constituent 1

Reference substance name:

5-hydroxy-4-propyl-2,5-dihydrofuran-2-one

Cas Number:

78920-10-2

Molecular formula:

C7H10O3

IUPAC Name:

5-hydroxy-4-propyl-2,5-dihydrofuran-2-one

Test material form:

liquid: viscous

Details on test material:

- Appearance: Brown viscous liquid
- Storage condition of test material: At room temperature

Results and discussion

Surface tension

Key result

Surface tension:

59.89 mN/m

Temp.:

20 °C

Conc.:

1 g/L

Any other information on results incl. tables

Surface Tension of the Test Item

Measurement	Time passed after measurement start [seconds]	Surface tension (mN/m)
		individual σ multiplied by Harkins-Jordan corrected value	mean σ^1
1	39.77	60.43	59.89
2	66.10	60.10
3	92.04	59.97
4	117.45	59.87
5	143.18	59.79
6	169.31	59.71

¹         Mean calculated from measurements 2 to 6, after equilibrium was reached.

Applicant's summary and conclusion

Conclusions:

The surface tension of an aqueous substance solution at a concentration of 1 g/L was determined to be 59.89 mN/m (at 20°C, OECD harmonized ring method).