Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

First-aid measures

General:

Pay attention to self-protection.

Remove victims from hazardous area.

Immediately remove soiled or soaked clothing and remove it to a safe distance.

Keep victim warm, in a stabilized position and covered.

Do not leave victims unattended.

If the casualty is unconscious: Place the victim in the recovery position.

Description of first aid measures:

Inhalation:

Potential for exposure by inhalation if aerosols or mists are generated.

After inhalation move subject to fresh air.

With labored breathing: Provide with oxygen. Consult a doctor.

If the casualty is not breathing: Perform mouth-to-mouth resuscitation, notify emergency physician immediately.

Skin Contact:       

Wash off affected area immediately with plenty of water for at least 15 minutes.

If symptoms persist, consult a physician for treatment.

Eye contact:

With eye held open, thoroughly rinse immediately with plenty of water for at least 10 minutes.

Inform emergency physician immediately (key term: caustic eye burn).

Ingestion:

Rinse mouth.

Immediately give large quantities of water to drink.

Inform emergency physician immediately.

Most important symptoms and effects, both acute and delayed:

Corrosive.

Indication of any immediate medical attention and special treatment needed:

Hazards:       

Strongly irritating to corrosive.

Treatment:

The initial focus is only on the local action, characterized by quickly progressing deep tissue damage.

Coughing is a symptom of a respiratory tract irritation after inhalation of aerosols or mists from caustic liquids.

In the eye, caustic liquids cause, depending on the intensity of exposure, severe irritation, destruction, and ablation of the epithelium of the conjunctiva and cornea, corneal clouding, edema and ulcerations.

Danger! Possible loss of eyesight!

Superficial irritations and damage up to ulcerations and scarring develop on the skin.

Fire-fighting measures

Extinguishing media:

Suitable extinguishing media:

All extinguishing substances suitable.

Unsuitable extinguishing media:

Do not use a solid water stream as it may scatter and spread fire.

Special hazards arising from the substance or mixture:

May be released in case of fire:

- Carbon monoxide

- Carbon dioxide

- Nitric oxides

Under certain fire conditions, traces of other toxic products may occur.

Advice for firefighters:

Special fire fighting procedures:

Contaminated extinguishing water must be treated at a suitable disposal plant in accordance with waste management laws.

In case of fire, remove the endangered containers and bring to a safe place, if this can be done safely.

Keep out unprotected persons.

Special protective equipment for fire-fighters:

In the event of fire, wear self-contained breathing apparatus. full protective suit.

Accidental release measures

Personal precautions, protective equipment and emergency procedures:

Keep unauthorized personnel away.

      

For non-emergency personnel:

No data available.

      

For emergency responders:

No data available.

Environmental Precautions:

Prevent substance from entering soil, natural bodies of water and sewer systems.

If the product contaminates rivers and lakes or drains inform respective authorities.

Methods and material for containment and cleaning up:

Pick up mechanically with a suitable material and collect in a suitable container.

Pack and label wastes like the pure substance.

Do not detach label from the delivery containers prior to disposal.

Disposal according to local authority regulations.

Handling and storage

Precautions for safe handling:

All precautionary measures indicated have to be observed.

Risk assessment and risk monitoring of all work places required.

Health, Safety and Emergency Management System recommended.

Written approval necessary in case of non-routine jobs, e.g. maintenance activities.

Regular safety training is a must.

Use permissible in closed systems only.

Handle and transfer product in closed systems only (gas displacement device).

Ensure that apparatus and pipelines are free from leaks.

Do not ventilate into the open.

Suitable loading and unloading device required.

The personal protective equipment used must meet the requirements of Regulation (EU) 2016/425 and amendments (CE certification).

It should be defined in the work place in the form of a risk analysis according to Regulation (EU) 2016/425 and amendments.

Conditions for safe storage, including any incompatibilities:

Normal measures for preventive fire protection.

Store in the original receptacle, keeping this tightly sealed, under cool and dry conditions.

Observe prohibition against storing together!

Protect from sunlight, warmth and heat.

In order to ensure due transportation, make certain that stacks are of the correct height, containers are securely fastened so as not to fall off, and labelled according to the regulations.

Storage Class:

12: Non-combustible liquids.

Transport information

Land transport (UN RTDG/ADR/RID)

UN number:
UN 1760
Shippingopen allclose all
Labels:
8
SpecialProvisionsopen allclose all

Inland waterway transport (UN RTDG/ADN(R))

UN number:
UN 1760
Shippingopen allclose all
Labels:
8
Remarksopen allclose all

Marine transport (UN RTDG/IMDG)

UN number:
UN 1760
Shipping information
Proper shipping name and description:
CORROSIVE LIQUID, N.O.S.
(Reaction mass of L-alanyl-L-tyrosine hydrochloride und potassium chloride)
Chemical name:
Reaction mass of L-alanyl-L-tyrosine hydrochloride und potassium chloride
Labels:
8
Remarksopen allclose all

Air transport (UN RTDG/ICAO/IATA)

UN number:
UN 1760
Shipping information
Proper shipping name and description:
Corrosive liquid, n.o.s.
(Reaction mass of L-alanyl-L-tyrosine hydrochloride und potassium chloride)
Chemical name:
Reaction mass of L-alanyl-L-tyrosine hydrochloride und potassium chloride
Labels:
8
Remarksopen allclose all
SpecialProvisionsopen allclose all

Exposure controls / personal protection

Control Parameters:

Occupational Exposure Limits:

None of the components have assigned exposure limits.

DNEL-Values:

Remarks: No substance-related safety assessment is necessary / has been conducted for this product.

PNEC-Values:

Remarks: No substance-related safety assessment is necessary / has been conducted for this product.

Exposure controls:

Appropriate Engineering Controls:

The substance must be handled under strictly controlled conditions in accordance with Article 17/18 of the REACH regulation.

Provide for installation of emergency shower and eye bath.

Refill and handle product only in closed system.

Leak detection recommended.

Do not add wastewater to a biological wastewater treatment plant.

Remove exhaust gases through a washer or through combustion.

Minimization of emissions by means of suitable technical measures such as flanges and valves with low leakage rates, recirculation of vapours.

All precautionary measures indicated have to be observed.

Individual protection measures, such as personal protective equipment:

Eye/face protection:

Safety glasses with side-shields conforming to EN166 or Accidental release measures close-fitting protective goggles (e.g. closed goggles).

Hand Protection:

Material: Nitrile

Glove thickness: 0.2 mm

Guideline: DIN EN 374

Accidental release measures:

Material: Nitrile/Chloroprene

Glove thickness: 0.65 mm

Guideline: DIN EN 374

Additional Information:

Selection of protective gloves to meet the requirements of specific workplaces.

Suitability for specific workplaces should be clarified with protective glove manufacturers.

The information is based on our own tests, references from the literature and information from glove manufacturers, or derived by analogy with similar materials.

Remember that the useful time per day of a chemical protection glove may be much shorter than the permeation time determined according to EN 374 due to the many different influential factors involved (e.g. temperature).

Skin and Body Protection:

Suitable protective clothing - Use disposable clothing if appropriate.

Respiratory Protection:       

Use suitable respiratory protection where aerosols/vapours are generated. Respirator with brown A-type filter. Accidental release measures: wear a self contained respiratory apparatus. Note time limit for wearing respiratory protective equipment.

Hygiene measures:

Do not eat, drink, smoke, or sniff while at work.

Wash your hands and/or face before breaks and before termination of work.

Avoid contact with eyes, skin, and clothing.

Take off contaminated clothing and wash it before reuse.

Preventive skin protection is recommended.

Use barrier cream regularly.

Environmental Controls:

In some cases, exhaust air scrubbers, filters or technical changes to the processing plant will be required in order to decrease emissions to acceptable values.

Stability and reactivity

Reactivity:

No data available.

Chemical Stability:

No data available.

Possibility of hazardous reactions:

No hazardous reactions are known if properly handled and stored.

Conditions to avoid:

Keep away from direct sunlight.

Incompatible Materials:

Strong acids and oxidizing agents.

Hazardous Decomposition Products:

No further information available.

Disposal considerations

Waste treatment methods:

General information:

No data available.

Disposal methods:

Strictly controlled conditions during disposal or treatment to air, wastewater and waste.

Do not add wastewater to a biological wastewater treatment plant.

Disposal according to local authority regulations.

Pack and label wastes like the pure substance.

Do not detach label from the delivery containers prior to disposal.

Contaminated Packaging:

Do not reuse empty containers and dispose of in accordance with the regulations issued by the appropriate local authorities.