Registration Dossier

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2019
Report Date:
2019

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 201 (Freshwater Alga and Cyanobacteria, Growth Inhibition Test)
GLP compliance:
yes (incl. certificate)

Test material

Reference
Name:
Unnamed
Type:
Constituent

Sampling and analysis

Analytical monitoring:
yes

Test solutions

Vehicle:
yes

Results and discussion

Effect concentrationsopen allclose all
Duration:
72 h
Dose descriptor:
NOEC
Effect conc.:
<= 1 mg/L
Duration:
72 h
Dose descriptor:
LOEC
Effect conc.:
>= 3.2 mg/L
Details on results:
The 72-hours EyC50 value for algae Pseudokirchneriella subcapitata exposed to 1,2,4,5-tetramethyl-1H-imidazole was 7.19 mg.L-1 and the 72-hours ErC50 value was not identified because the highest concentration tested 100 mg.L-1 caused only 35% inhibition of growth rate. The highest test item concentration with no observed significant adverse effect (NOEC) on algal growth was 1 mg.L-1 and the lowest test item concentration at which was observed significant reducing effect on growth (LOEC) was 3.2 mg.L-1.

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
72-hours EyC50=7.19 mg.L-1