Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
hydrolysis
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Reference
Reference Type:
review article or handbook
Title:
Maleic Anhydride and Maleic Acid, SIDS Initial Assessment Report For SIAM 18
Author:
OECD SIDS
Year:
2004
Bibliographic source:
OECD SIDS Initial Assessment Report For SIAM 18, 20-23 April 2004

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
No guideline available found in the published report.
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Maleic anhydride
EC Number:
203-571-6
EC Name:
Maleic anhydride
Cas Number:
108-31-6
Molecular formula:
C4H2O3
IUPAC Name:
2,5-dihydrofuran-2,5-dione

Results and discussion

Preliminary study:
not available
Transformation products:
yes
Identity of transformation products
Reference
Reference substance name:
Unnamed
IUPAC name:
Maleic Acid
Inventory number:
InventoryMultipleMappingImpl [inventoryEntryValue=EC 203-742-5]
CAS number:
110-16-7
Dissipation DT50 of parent compound
Temp.:
25 °C
DT50:
22 s

Applicant's summary and conclusion

Conclusions:
In the presence of water, maleic anhydride rapidly hydrolyzes to form maleic acid. The half-life of the
hydrolysis of maleic anhydride to maleic acid in water at 25oC has been determined to be approximately 22 seconds.