Registration Dossier
Registration Dossier
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EC number: 200-526-2 | CAS number: 62-23-7
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vitro / ex vivo
- Type of information:
- (Q)SAR
- Remarks:
- QSAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- QSAR
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 019
- Report date:
- 2019
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- QSAR
- GLP compliance:
- no
Test material
- Reference substance name:
- 4-nitrobenzoic acid
- EC Number:
- 200-526-2
- EC Name:
- 4-nitrobenzoic acid
- Cas Number:
- 62-23-7
- Molecular formula:
- C7H5NO4
- IUPAC Name:
- 4-nitrobenzoic acid
- Test material form:
- solid: crystalline
Constituent 1
Results and discussion
In vitro
Results
- Irritation parameter:
- other: QSAR
- Remarks on result:
- positive indication of irritation
- Remarks:
- QSAR
Applicant's summary and conclusion
- Interpretation of results:
- Category 2 (irritating to eyes) based on GHS criteria
- Conclusions:
- Prediction EYE IRRITANT, based on probability of severe/moderate irritation equal to 0.73.
- Executive summary:
Prediction EYE IRRITANT, based on probability of severe/moderate irritation equal to 0.73.
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