Registration Dossier
Registration Dossier
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EC number: 605-140-1 | CAS number: 158237-07-1
Endpoint summary
Administrative data
Description of key information
Additional information
In a screening study according to EU Method C.4-E (1999) with activated sludge 0% biodegradation was observed, thus the test substance has to be considered as not readily biodegradable. Further simulation studies with paddy soils investigated the biodegradation potential of the substance (1995, 1997b). Under the laboratory conditions chosen (experiments were conducted at 28 °C) these studies resulted in a maximum half-life of 46 days.
However, according to the ECHA document "Guidance on Information Requirements and Chemical Safety Assessment. Chapter R.7b: Endpoint specific guidance. Version 4.0" (2017) the preferred temperature for simulation degradation studies is 12 °C, which corresponds to average temperature of European surface waters. Where this condition is not met a temperature correction should be considered based on the Arrhenius equation and half-lives be re-calculated. For first order kinetics this was done and the half-life of 46 days (at 28 °C) was re-calculated to 199 days (at 12 °C), respectively.
The available simulation data on soil biodegradation gained in studies with paddy soils systems are reflecting similar conditions as in water/sediment tests. No alternative metabolism pathway is expected in a new biodegradation simulation study in water/ sediment than in the biodegradation study in soil.
Thus, based on a worst case assumption the test substance has to be regarded as being very persistent.
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