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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
GLP compliance:
no
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Constituent 1
Reference substance name:
Amaryllidaceae, Allium Cepa L. (fresh bulb), Rutaceae, Citrus Limon (L.) Burm. F. (fresh pulp), extract, sodium chloride
EC Number:
944-860-3
IUPAC Name:
Amaryllidaceae, Allium Cepa L. (fresh bulb), Rutaceae, Citrus Limon (L.) Burm. F. (fresh pulp), extract, sodium chloride
Test material form:
solid

Study design

Analytical method:
high-performance liquid chromatography

Results and discussion

Partition coefficientopen allclose all
Key result
Type:
log Pow
Partition coefficient:
< 0.3
Temp.:
25 °C
Remarks on result:
other: UVCB substance: peaks 1, 2 and 3 has logPow <0.3
Key result
Type:
log Pow
Partition coefficient:
ca. 0.715
Temp.:
25 °C
Remarks on result:
other: UVCB substance: peak 4 has logPow ca. 0.715

Applicant's summary and conclusion

Executive summary:

The partition coefficient study was performed according to the OECD 117.

The chromatogram of the test substance solution showed 4 peaks.

The first three peaks lie within the dead time of the method and not within the range of log POWs of the reference substances. Therefore, the corresponding logP are stated as < 0.3 for peaks 1, 2, and 3. Using the correlation log k / logP, the logP of peak 4 of the test substance EXTRACT OF ALLIUM CEPA (AMARYLLIDACEAE) BULB AND CITRUS LIMON (RUTACEAE) PULP AND SODIUM CHLORIDE was calculated as 0.715 ± 0.000(mean ± standard deviation),determined at 25 ± 0.5°C and at pH 7, measured with pH paper.