Registration Dossier
Registration Dossier
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EC number: 618-920-1 | CAS number: 93280-40-1
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The substance is acutely harmful to fish.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 58 mg/L
Additional information
Data on the acute toxicity of vanadylhydrogenphosphate-hemihydrate (CAS no. 93280-40-1) to fish are not available; therefore, a read-across approach to the structurally similar substance divanadyl pyrophosphate (CAS 65232-89-5; Catalyst E-326) was performed. The reliable guideline study followed OECD 203 with Catalyst E-326 as test item. The study was performed under GLP. The test species was Oncorhynchus mykiss (rainbow trout). The test system was static. Five test concentrations were prepared in a range between 100 and 1000 mg/L test material. The test concentrations were analytically verified by Atomic Absorption Spectrometry for the vanadium content with and without filtration (0.2 µm) of the test solutions. At all concentration levels undissolved test material was visible in suspension and on the bases of the test vessels. During the test undissolved test material settled out of suspension. The 96-h LC50 was determined to be 51.8 mg/L (test material; meas., filtered). Based on the vanadium concentration the 96-h LC50 is 17 mg/L (meas., filtered).
For the assessment of the toxicity of vanadylhydrogenphosphate-hemihydrate (CAS no. 93280-40-1), the effect value based on the vanadium concentration must be corrected for the molecular weight of vanadylhydrogenphosphate-hemihydrate (29.4% V). The corrected 96-h LC50 is 58 mg/L (= 17 mg V/L).
It can be concluded that the substance is acutely harmful to fish.
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