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Toxicological information

Skin sensitisation

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Administrative data

Endpoint:
skin sensitisation: in vivo (non-LLNA)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2006
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2006
Report date:
2006

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
the objective of this study was to determine the irritation and/or sensitization potential of the test article after repeated application under occlusive patch test conditions to the skin of human subjects (non-exclusive panel).
GLP compliance:
yes
Type of study:
patch test
Justification for non-LLNA method:
An HRIPT test was performed in 2006 without any positive result. So there was no need to perform non LLNA method test

Test material

Constituent 1
Chemical structure
Reference substance name:
Tri(tridecyl) benzene-1,2,4-tricarboxylate
EC Number:
302-446-4
EC Name:
Tri(tridecyl) benzene-1,2,4-tricarboxylate
Cas Number:
94109-09-8
Molecular formula:
C48H84O6
IUPAC Name:
tri(tridecyl) benzene-1,2,4-tricarboxylate
Test material form:
liquid
Details on test material:
- Moisture content: <= 0.1%

In vivo test system

Study design: in vivo (non-LLNA)

Challenge controls:
none
Positive control substance(s):
no

Results and discussion

Positive control results:
no

In vivo (non-LLNA)

Resultsopen allclose all
Key result
Reading:
rechallenge
Hours after challenge:
48
Group:
test chemical
Dose level:
0.2 mL
No. with + reactions:
0
Total no. in group:
51
Key result
Reading:
rechallenge
Hours after challenge:
24
Group:
test chemical
Dose level:
0.2 mL
No. with + reactions:
0
Total no. in group:
51
Key result
Reading:
2nd reading
Hours after challenge:
48
Group:
test chemical
Dose level:
0.2 mL
No. with + reactions:
0
Total no. in group:
51
Key result
Reading:
1st reading
Hours after challenge:
24
Group:
test chemical
Dose level:
0.2 mL
No. with + reactions:
0
Total no. in group:
51

Applicant's summary and conclusion