Reaction products of 2-hydroxy-6-nitro-4-sulphonaphthalene-1-diazonium coupled with resorcinol, subsequently coupled with diazotised 5-amino-2-anilinobenzenesulphonic acid, iron(III) complexes, sodium salts

Endpoint summary

Description of key information

LD50 oral rat>2000 mg/Kg bw

Key value for chemical safety assessment

Acute toxicity: via oral route

Link to relevant study records

Reference

Endpoint:

acute toxicity: oral

Type of information:

other: expert statement

Adequacy of study:

weight of evidence

Study period:

2019

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Justification for type of information:

For more information see document attached in section 13. (Collection of information for weight of evidence approach – “Information on WoE”)

Reason / purpose for cross-reference:

read-across: supporting information

Guideline:

other: REACH GUIDANCE ON WOE

GLP compliance:

no

Key result

Dose descriptor:

LD50

Effect level:

> 2 000 mg/kg bw

Based on:

test mat.

Interpretation of results:

GHS criteria not met

Executive summary:

Based on overall information LD50 is higher than 2000 mg/Kg bw

Endpoint conclusion

Endpoint conclusion:

no adverse effect observed

Acute toxicity: via inhalation route

Endpoint conclusion

Endpoint conclusion:

no study available

Acute toxicity: via dermal route

Endpoint conclusion

Endpoint conclusion:

no study available

Justification for classification or non-classification

Based on conclusion coming from a weight of evidence assessment, LD50 is estimated to be >2000 mg/Kg bw. No classification for acute toxicity oral is warranted under Regulation 1272/2008.