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Density

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Reference
Endpoint:
density, other
Remarks:
Density
Type of information:
experimental study
Adequacy of study:
key study
Study period:
02 August to 03 August 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 109 (Density of Liquids and Solids)
Version / remarks:
October 2012
Deviations:
no
GLP compliance:
yes
Type of method:
pycnometer method
Specific details on test material used for the study:
SOURCE OF TEST MATERIAL
- Source and lot/batch No. of test material: Batch number: A0076
- Expiration date of the lot/batch: 2021
- Purity test date: Not specified

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: Ambient (15 +/- 10°C), in the dark
- Stability under test conditions: 20 +/- °C
- Solubility and stability of the test substance in the solvent/vehicle: Stable
- Reactivity of the test substance with the solvent/vehicle of the cell culture medium: Not specified



Key result
Type:
density
Density:
1.143 g/cm³
Temp.:
22.3 °C

  Table 1: The calculated density for the reaction mass of amines, hydrogenated tallow alkyl and azelaic acid and lithium hydroxide.

Reaction mass of amines, hydrogenate tallow alkyl and azelaic acid and lithium hydroxide

 

Replicate 1

Replicate 2

Replicate 3

Pnv(ml)

25.0379

25.0379

25.0379

PnDw(g)

22.5166

22.5166

22.5166

PnDFw(g)

42.0938

42.0771

42.0785

DFtw(g)

19.5772

19.5605

19.5619

DFd(g/cm3)

0.7819

0.7812

0.7813

PnSw(g)

23.5132

23.3036

23.3279

PnDFSw(g)

42.3829

42.3358

42.3441

DFw(g)

18.8697

19.0322

19.0162

DFv(ml)

24.1331

24.3628

24.3392

Sv(ml)

0.9048

0.6751

0.6987

Sd(g/cm3)

1.1015

1.1658

1.1612

Mean density (g/cm3)±

5% acceptance limits

                  1.1428± 0.0571

Where:

DFv = Volume of displacement fluid in pycnometer

Sv = Sample volume

Pnv = Quoted pycnometer volume

Sd = Sample density

PnSw = Weight of pycnometer with sample

Conclusions:
The density of the test item was determined to be 1.1428 g/cm3 at 22.3°C.
Executive summary:

Crane J (2018) is a GLP-compliant study following OECD guideline 109 and is therefore reliable without restrictions (Klimisch 1). The pycnometer method was used to determine density of the test item. The measurements were performed in triplicate.

The density of the test item was determined to be 1.1428g/cm3 at 22.3°C. The test is considered valid as all three replicates were found to be within the ±5% of the average density for the test.

Description of key information

The density of the test item was determined to be 1.1428 g/cm3 at 22.3°C.

Key value for chemical safety assessment

Relative density at 20C:
1.143

Additional information

The density study was conducted following OECD guideline 109 and is GLP-compliant and therefore reliable without restrictions (Klimisch 1). The pycnometer method was used to determine density of test item.