Registration Dossier
Registration Dossier
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EC number: 243-835-8 | CAS number: 20457-75-4
Endpoint summary
Administrative data
Description of key information
skin irritating (ivt, OECD 439/431),
eye irritating (ivt, OECD 492)
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Justification for classification or non-classification
Local toxicity of N-[3-(dimethylamino)propyl]-12-hydroxyoctadec-9-enamide has been assessed in vitro.
The skin irritation has been observed (OECD 439) but the skin corrosion test (OECD 431) was negative. These results meet the criteria for classification Skin Irritation 2 acoording to Regulation (EC) No 1272/2008.
Eye irritation has been observed (OECD 492). The EpiOcular test cannot resolve between classification Catergories 1 and 2. Thus, acoording to Regulation (EC) No 1272/2008 the worst case classification Eye Damage 1 is considered appropriate.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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