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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
(Q)SAR
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Justification for type of information:
Please refer to QPRF/QMRF documentation for detailed information on model suitability.

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
BIOWIN v4.10 (September 2010)
Author:
US EPA
Year:
2010
Bibliographic source:
United States Environmental Protection Agency, Washington, DC, USA.
Reference Type:
other: Estimation software
Title:
Estimation Programs Interface Suite for Microsoft Windows, v4.11
Author:
US EPA
Year:
2012
Bibliographic source:
United States Environmental Protection Agency, Washington DC, USA; November 2012
Reference Type:
publication
Title:
Group contribution method for predicting probability and rate of aerobic biodegradation.
Author:
Boethling, R.S., Howard, P.H., Meylan, W., Stiteler, W., Beaumann, J., Tirado, N.
Year:
1994
Bibliographic source:
Environ. Sci. Technol. 28:459-65.

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: REACH guidance on information requirements and chemical safety assessment, chapter R.6: QSARs and grouping of chemicals.
Version / remarks:
May 2008
Principles of method if other than guideline:
(Q)SAR calculation: EPIWEB V4.1 - Biowin V 4.10
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
N-(carbamoylmethyl)taurine
EC Number:
230-908-4
EC Name:
N-(carbamoylmethyl)taurine
Cas Number:
7365-82-4
Molecular formula:
C4H10N2O4S
IUPAC Name:
N-(carbamoylmethyl)taurine
Test material form:
solid
Specific details on test material used for the study:
SMILES : O=C(N)CNCCS(=O)(=O)O
MOL FOR: C4 H10 N2 O4 S1
MOL WT : 182.20

Results and discussion

% Degradation
Key result
Parameter:
other: Ready Biodegradability Prediction: NO
Remarks on result:
other: QSAR calculation (BIOWIN)
Details on results:
Biowin1 (Linear Biodeg Probability) = 1.1332
Biowin2 (Non-Linear Biodeg Probability) = 1.0000
Biowin3 (Survey Model - Ultimate Biodeg) = 2.9594
Biowin4 (Survey Model - Primary Biodeg) = 4.0107
Biowin5 (MITI Linear Biodeg Probability) = 0.4783
Biowin6 (MITI Non-Linear Biodeg Probability) = 0.3006
Biowin7 (Anaerobic Linear Biodeg Prob) = 0.5235

Any other information on results incl. tables

Biowin1 (Linear Model Prediction) : Biodegrades Fast

Biowin2 (Non-Linear Model Prediction): Biodegrades Fast

Biowin3 (Ultimate Biodegradation Timeframe): Weeks

Biowin4 (Primary Biodegradation Timeframe): Days

Biowin5 (MITI Linear Model Prediction) : Does Not Biodegrade Fast

Biowin6 (MITI Non-Linear Model Prediction): Does Not Biodegrade Fast

Biowin7 (Anaerobic Model Prediction): Biodegrades Fast

Ready Biodegradability Prediction: NO

Applicant's summary and conclusion

Validity criteria fulfilled:
not applicable
Interpretation of results:
not readily biodegradable
Conclusions:
N-(carbamoylmethyl) taurine is predicted to not be readily biodegradable by the (Q)SAR model BIOWIN v4.10.
Executive summary:

N-(carbamoylmethyl) taurine is predicted to not be readily biodegradable by the (Q)SAR model BIOWIN v4.10.