Registration Dossier

Administrative data

Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report Date:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
other: EC Guideline A.2. Boiling Temperature. March 04, 2016
Deviations:
no
Qualifier:
according to
Guideline:
OECD Guideline 103 (Boiling Point)
Deviations:
no
Qualifier:
according to
Guideline:
EPA OPPTS 830.7220 (Boiling Point / Boiling Range)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
differential scanning calorimetry

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder
Details on test material:
Dry powder, white to slightly yellow
Specific details on test material used for the study:
Appearance: White to slightly yellow powder
Batch: Q0926501
Purity/Composition: 99.3%
Test item storage: At room temperature protected from light
Stable under storage conditions until: 30 November 2019 (expiry date)

Results and discussion

Boiling point
Key result
Boiling pt.:
> 150 °C
Atm. press.:
ca. 1 013.25 hPa
Remarks on result:
other: reaction and/or decomposition of the test item at > 150°C (> 423K) was observed

Any other information on results incl. tables

An endothermic effect was observed between 25°C and 125°C followed by a broad endothermic effect starting at 150°C. The endothermic effect was most likely obtained due to melting of the test item. The second endothermic effect was probably obtained due to reaction and/or decomposition of the test item.

After the experiment, a dark brown molten residue remained in the sample container (original colour: white to slightly yellow). The change of the colour indicated reaction and/or decomposition of the test item. Based on this visual observation, it was found that the test item had molten and the change of the colour demonstrated reaction and/or decomposition of the test item.

Applicant's summary and conclusion

Conclusions:
Based on this result, the test item has a boiling point > 150°C at 1013.25 hPa.
Executive summary:

The boiling temperature of D-Ribose was tested by DSC according to OECD 103 guideline study.

Reaction and/or decomposition of the test item was observed during DSC experiment at temperatures of > 150°C (> 423K). Boiling of the test item was not observed below the temperature at which reaction and/or decomposition started.