Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 218-657-9 | CAS number: 2212-10-4
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
Data source
Reference
- Reference Type:
- other: Secondary source
- Title:
- Unnamed
- Year:
- 1 986
Materials and methods
Test guideline
- Guideline:
- other: not specified
- Principles of method if other than guideline:
- Not specified.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- (chloromethyl)diethoxymethylsilane
- EC Number:
- 218-657-9
- EC Name:
- (chloromethyl)diethoxymethylsilane
- Cas Number:
- 2212-10-4
- Molecular formula:
- C6H15ClO2Si
- IUPAC Name:
- (2-chloro-1,1-diethoxyethyl)silane
- Test material form:
- liquid
- Details on test material:
- Unknown purity; test material used in published study; no information on grade or analytical data included.
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- other: inhalation. no data available whether exposure was via gas, aerosol or vapor.
- Type of inhalation exposure:
- not specified
- Vehicle:
- not specified
- Details on inhalation exposure:
- no data
- Analytical verification of test atmosphere concentrations:
- not specified
- Duration of exposure:
- 4 h
- Concentrations:
- 2270 ppm; no data available whether other concentrations were tested as well.
- No. of animals per sex per dose:
- no data
- Control animals:
- not specified
- Statistics:
- no data
Results and discussion
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- LCLo
- Effect level:
- 2 270 ppm
- Based on:
- not specified
- Remarks on result:
- other: Details of toxic effects not reported other than lethal dose value.
- Mortality:
- yes, but no details available
- Clinical signs:
- other: no data
- Body weight:
- no data
- Gross pathology:
- no data
Any other information on results incl. tables
No data available.
Applicant's summary and conclusion
- Interpretation of results:
- study cannot be used for classification
- Conclusions:
- In a RTECS data entry (reliability score 4) for Silane, chloromethylmethyldiethoxy- a LCLo of 2270 ppm/4h was recorded. No further details are available.
- Executive summary:
In a RTECS data entry (reliability score 4) for Silane, chloromethylmethyldiethoxy- a LCLo of 2270 ppm/4h was recorded. No further details are available.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
