Registration Dossier

Administrative data

First-aid measures

General information: When seeking medical attention, show this material safety data sheet or the packing with the label.
After inhalation: Immediately remove patient from exposure and move to fresh air. Rinse mouth and nose with water. Obtain medical attention if irritation persists.
After skin contact: Remove contaminated clothing. Wash affected area with plenty of water and soap. Obtain medical attention if irritation persists.
After eye contact: Remove contact lenses if any. Immediately rinse affected eye(s) with water for up to 15 minutes. Obtain medical attention if irritation/discomfort persists.
Continue to rinse with water during transport.
After swallowing: Flush mouth with water and give milk or water to conscious person. Try to induce vomiting. Obtain medical attention. In case of unconsciousness provide
artificial respiration.

Fire-fighting measures

Suitable extinguishing agents: Extinguish fire with water, dry chemical, CO2 or foam.
Special hazards arising from the substance or mixture Formation of toxic and corrosive gases is possible during heating or in case of The substance is combustible and the dust may form explosive mixtures with air.
Protective equipment: A self-contained breathing apparatus and full protective clothing should be worn when fighting the fire.
Additional information Evacuate area.
Remove substance/product from fire threatened area, if possible.
Stop leakage. Water from extinction of fires may be hazardous waste. Must not enter sewage or water systems.
Avoid inhalation of fumes. Persons who have inhaled fumes must obtain medical attention (risk of delayed lung oedema).

Accidental release measures

Personal precautions, protective equipment and emergency procedures Use respirator, protective gloves and goggles/face shield during clean-up.
Avoid contact with skin and eyes and inhalation of dust.
Environmental precautions: Do not allow product to reach sewage system or any water course.
Methods and material for containment and cleaning up: Small release: Wipe up spillages with moist cloth or paper.
Major release: Pick up mechanically and dispose of according to regulation on hazardous waste.
Dust generation may be reduced by carefully moistering or by covering with plastic film.
Wash the spillage area with plenty of water, and prevent entry into drains.

Handling and storage

Precautions for safe handling Persons, who handle this material, should be familiar with the hazards of the material and the necessary safety precautions, including this safety data sheet.
Pregnant and breast feeding women should not be exposed to the substance.
Persons under 18 years of age may not work with or be exposed to the substance.
The substance should preferable be used in closed systems and be handled under well-ventilated conditions.
Immediately remove contaminated clothes.
Wash hands after work, before eating and after using the bathroom.
Avoid inhalation of dust. Avoid contact with skin and eyes. Avoid prolonged and/or repeated exposure.
Prevent formation of dust.
Information about fire - and explosion
protection: If hazardous, explosive atmospheres may form, the work area must be classified and organised according to the regulations on hazardous, explosive
atmosphere. All work must be carried out in compliance with these regulations.
Dust can combine with air to form an explosive mixture (dust explosion).
Storage: Store in a well-closed container.

Transport information

Land transport (UN RTDG/ADR/RID)

UN number:
3077
Shipping information
Proper shipping name and description:
3077 ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. ((R)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl) benzonitrile)
Chemical name:
(R)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl) benzonitrile)
Labels:
9
SpecialProvisionsopen allclose all

Inland waterway transport (UN RTDG/ADN(R))

UN number:
3077
Shipping information
Proper shipping name and description:
3077 ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. ((R)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl) benzonitrile)
Chemical name:
(R)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl) benzonitrile)
Labels:
9
Remarksopen allclose all

Marine transport (UN RTDG/IMDG)

UN number:
3077
Shipping information
Proper shipping name and description:
3077 ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. ((R)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl) benzonitrile)
Chemical name:
(R)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl) benzonitrile)
Labels:
9
Remarksopen allclose all

Air transport (UN RTDG/ICAO/IATA)

UN number:
3077
Shipping information
Proper shipping name and description:
3077 ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. ((R)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl) benzonitrile)
Chemical name:
(R)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl) benzonitrile)
Labels:
9
Remarksopen allclose all
SpecialProvisionsopen allclose all

Exposure controls / personal protection

The substance is used under strictly controlled condition (SCC) during its whole lifecycle:
(a) the substance is rigorously controlled from its arrival to its use and transformation:
(b) procedural (Standard Operating Procedures for use) and control technologies are used to minimize emission and any resulting exposure;
(c) the substance is handled only by trained and authorized personnel;
(d) in the case of cleaning and maintenance works, special procedures such as equipment washing are applied before the system is opened and entered;
(e) in cases of accident and where waste is generated, there is an Emergency Plan to minimize emissions and the resulting exposure;
(f) substance-handling procedures are well documented and strictly supervised by the site operator.

Stability and reactivity

Chemical stability Stable at normal temperature and pressure.
Possibility of hazardous reactions The substance is expected to be combustible. Dust may form explosive mixtures with air.
Conditions to avoid No further relevant information available.
Incompatible materials: No further relevant information available.
Hazardous decomposition products: Formation of toxic and corrosive gases is possible during heating or in case of fire (COx, NOx).

Disposal considerations

The product should be disposed of according to local regulations.