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Physical & Chemical properties

Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
other: read across
Adequacy of study:
supporting study
Study period:
June 23rd, 2015
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Principles of method if other than guideline:
Laser light scattering. The test was performed according to the SOP - STR 071 protocol.
The particle size distribution was analyzed using the Mastersizer 2000 tool, which uses the technique of laser diffraction to measures the size of particles. It measures the intensity of light scattered as a laser beam passes through a dispersed particulate sample. This data is then analyzed to calculate the size of the particles that created the scattering pattern.
GLP compliance:
no
Type of method:
Laser scattering/diffraction
Type of distribution:
volumetric distribution
Percentile:
D50
Mean:
28.405 µm
Remarks on result:
other: Analysis carried out after 2 minutes of ultrasonic treatment.
Percentile:
D10
Mean:
6.613 µm
Remarks on result:
other: Analysis carried out after 2 minutes of ultrasonic treatment.
Percentile:
D90
Mean:
83.94 µm
Remarks on result:
other: Analysis carried out after 2 minutes of ultrasonic treatment.
Conclusions:
d(0.5): 28.405 µm
Executive summary:

The particle size distribution was analyzed using the Mastersizer 2000 tool, which uses the technique of laser diffraction to measures the size of particles. It measures the intensity of light scattered as a laser beam passes through a dispersed particulate sample. This data is then analyzed to calculate the size of the particles that created the scattering pattern.

Analysis carried out after 2 minutes of ultrasonic treatment:

d(0.1): 6.613 µm

d(0.5): 28.405 µm

d(0.9): 83.940 µm

Conclusion

d(0.1): 6.613 µm

d(0.5): 28.405 µm

d(0.9): 83.940 µm

Description of key information

MMD: 28.405 µm

Additional information

Laser light scattering