Registration Dossier
Registration Dossier
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EC number: 429-630-8 | CAS number: -
Basic toxicokinetics
Administrative data
- Endpoint:
- basic toxicokinetics, other
- Adequacy of study:
- other information
Data source
Materials and methods
- Objective of study:
- toxicokinetics
Test material
- Test material form:
- liquid
- Details on test material:
- Name of test material (as cited in study report): Eldew PS-203
Physical state: pale yellow, oily liquid
Analytical purity: 100%
Purity test date: not reported
Lot/batch No.: 808010
Expiration date of the lot/batch: 31.03.2000
Storage condition of test material: test material was stored at room temperature (ca. 20°C), away from direct sunlight
Constituent 1
Results and discussion
Applicant's summary and conclusion
- Conclusions:
- Studies dealing specifically with toxicokinetic behaviour are not available.
From an acute oral toxicity test in rats a LD50 value of > 2000 mg/kg bw was derived. At this dose level no deaths or signs of intoxication were observed indicating no significant resorption or toxicity of the substance.
From an acute dermal toxicity test in rats a LD50 value of > 2000 mg/kg bw was derived. At this dose level no deaths or signs of intoxication were observed indicating no significant resorption or toxicity of the substance.
In a 28-day study rats were dosed with up to 1000 mg/kg bw/d. No deaths or signs of intoxication were observed.
All of these studies are indicating that the test item is not or negligibly resorbed. - Executive summary:
Studies dealing specifically with toxicokinetic behaviour are not available.
From an acute oral toxicity test in rats a LD50 value of > 2000 mg/kg bw was derived. At this dose level no deaths or signs of intoxication were observed indicating no significant resorption or toxicity of the substance.
From an acute dermal toxicity test in rats a LD50 value of > 2000 mg/kg bw was derived. At this dose level no deaths or signs of intoxication were observed indicating no significant resorption or toxicity of the substance.
In a 28-day study rats were dosed with up to 1000 mg/kg bw/d. No deaths or signs of intoxication were observed.
All of these studies are indicating that the test item is not or negligibly resorbed.
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