Registration Dossier
Registration Dossier
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EC number: 203-251-6 | CAS number: 104-91-6
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because a long-term aquatic toxicity study on invertebrates is available
- Justification for type of information:
- Data for 21 day reprodution study taken from a review of nitro-phenol substances and EC0 > 1 mg/l
In view of biodegradation results, classification is not required on this basis
4-Nitrophenol considered suitable for read-across potential for toxicity the oxidation form of the nitrogen is not critical for short term toxic effects
Cross-reference
- Reason / purpose for cross-reference:
- data waiving: supporting information
Reference
- Endpoint:
- long-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 21 day reproduction
- Reliability:
- 2 (reliable with restrictions)
- Justification for type of information:
- Data for 21 day reprodution study taken from a review of nitro-phenol substances and EC0 > 1 mg/l
In view of biodegradation results, classification is not required on this basis
4-Nitrophenol considered suitable for read-across potential for toxicity the oxidation form of the nitrogen is not critical for short term toxic effects - Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 211 (Daphnia magna Reproduction Test)
- GLP compliance:
- not specified
- Analytical monitoring:
- not specified
- Test organisms (species):
- Daphnia magna
- Test type:
- not specified
- Water media type:
- freshwater
- Total exposure duration:
- 21 d
- Hardness:
- Not specified in review
- Test temperature:
- Not specified in review
- pH:
- Not specified in review
- Dissolved oxygen:
- Not specified in review
- Duration:
- 21 d
- Dose descriptor:
- NOEC
- Effect conc.:
- ca. 1 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- reproduction
- Duration:
- 21 d
- Dose descriptor:
- LOEC
- Effect conc.:
- ca. 1.3 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- reproduction
- Details on results:
- No further details
- Validity criteria fulfilled:
- not specified
- Executive summary:
Data for 21 day reprodution study taken from a review of nitro-phenol substances and EC0 > 1 mg/l
In view of biodegradation results, classification is not required on this basis
4-Nitrophenol considered suitable for read-across potential for toxicity the oxidation form of the nitrogen is not critical for short term toxic effects
Data source
Materials and methods
Results and discussion
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
