2-Propenoic acid, ethyl ester, reaction products with mixed substituted alkyl esters of phosphorodithioic acid and propylene oxide

Vapour pressure

Link to relevant study record(s)

Reference

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

18 Sep 2017 - 08 Jan 2018

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Version / remarks:

2009

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Version / remarks:

2006

Deviations:

no

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7950 (Vapor Pressure)

Version / remarks:

1996

Deviations:

no

GLP compliance:

yes

Type of method:

effusion method: isothermal thermogravimetry

Specific details on test material used for the study:

Decomposition temp.: 150°C

Key result

Temp.:

20 °C

Vapour pressure:

0.036 Pa

Key result

Temp.:

25 °C

Vapour pressure:

0.055 Pa

Table: Results of the isothermal TGA analysis (test item)

Experiment	Temperature	Weight loss [µg/min]	νT [g/cm2/h]	log νT	log PT	PT [Pa]
1(^1)	70	0.793608	9.47x10^-5	-4.02	-0.01	0.97
	80	1.38327	1.65x10^-4	-3.78	0.30	2.0
	90	2.20965	2.64x10^-4	-3.50	0.56	3.6
	100	3.21250	3.83x10^-4	-3.42	0.76	5.8
2	70	0.893306	1.07x10^-4	-3.97	0.05	1.1
	80	1.60912	1.92x10^-4	-3.72	0.38	2.4
	90	2.65990	3.14x10^-4	-3.50	0.65	4.5
	100	3.84558	4.59x10^-4	-3.34	0.86	7.3
3	70	1.09245	1.30x10^-4	-3.88	0.16	1.5
	80	1.78942	2.14x10^-4	-3.67	0.44	2.7
	90	2.63240	3.18x10^-4	-3.50	0.66	4.6
	100	3.60903	4.31x10^-4	-3.37	0.83	6.7

(1) Experiment 1 was not used in calculation.

The vapour pressure regression curve constructed using the data of Experiment 1 and Experiment 2 had a coefficient of correlation of <0.99. Therefore, it was decided to perform a third experiment and to calculate the coefficient of correlation for the Experiment 1/Experiment 2/Experiment 3, Experiment 1/Experiment 2, Experiment 1/Experiment 3 and Experiment 2/Experiment 3. Only the coefficient of correlation for the Experiment 2/Experiment 3 was >0.99. Based on this, the results from Experiment 1 were excluded.

Conclusions:

The vapour pressure of the substance at 20°C was determined to be 3.6E-2 Pa.
The vapour pressure of the substance at 25°C was determined to be 5.5E-2 Pa.

Executive summary:

The vapour pressure of the substance was determined using the isothermal thermogravimetric effusion method in a GLP study according to EC A.4, OECD 104 and OPPTS 830.7950.

The constants specific for the experimental arrangement were determined using a set of 5 reference compounds. A vapour pressure curve for the test item was constructed from duplicate measurements at 70°C, 80°C, 90°C and 100°C. The vapour pressure of the substance at 20°C and 25°C was determined by extrapolation to be 3.6E-2 Pa and 5.5E-2 Pa, resp.

 

Description of key information

The vapour pressure of the substance at 20°C was determined to be 3.6E-2 Pa.

The vapour pressure of the substance at 25°C was determined to be 5.5E-2 Pa.

Key value for chemical safety assessment

Vapour pressure:

0.055 Pa

at the temperature of:

25 °C