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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Reference
Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Study period:
48 hours
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Justification for type of information:
Marine study performed to guidelines in 2002 to GLP.
Suporting analysis not performed, but it is considered that in view of known water solubility and known stability, the results are valid.
Qualifier:
according to
Guideline:
OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
Version / remarks:
Marine species
GLP compliance:
yes (incl. certificate)
Specific details on test material used for the study:
Commercial grade material used. Results are reported as 50% commercial grade.
Analytical monitoring:
no
Vehicle:
no
Test organisms (species):
other: Acartia tonsa
Details on test organisms:
Approx 14 days old at time of test.
Test type:
static
Water media type:
saltwater
Limit test:
no
Total exposure duration:
48 h
Test temperature:
19 - 21 C
Dissolved oxygen:
ca 7 mg/l
Salinity:
Standard seawater
Nominal and measured concentrations:
Nominal 0, 100, 300, 900, 2700 mg/l as 50% active material as supplied.
Reference substance (positive control):
yes
Remarks:
3,5-dichlorophenol
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
ca. 775 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
ca. 380 mg/L
Nominal / measured:
nominal
Conc. based on:
act. ingr.
Basis for effect:
mortality
Details on results:
There was complete mortality at 900 and 2700 mg/l, but no effect at 300 mg/l.
Results with reference substance (positive control):
Valid
Validity criteria fulfilled:
yes
Conclusions:
Although thre was no confirmatory analysis, the result is conclusive that classification is not needed as a result of this work
The substance is supplied and used in water.

Description of key information

Figure cited is estimated for the active ingredient based on use of test material with ca 50% actives

Key value for chemical safety assessment

EC50/LC50 for marine water invertebrates:
380 mg/L

Additional information