Reaction mass of aluminium and magnesium oxide and spinel (Mg(AlO2)2)

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:

toxicity to aquatic algae and cyanobacteria

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: GLP guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2010

Report date:

2010

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 201 (Alga, Growth Inhibition Test)

GLP compliance:

yes (incl. QA statement)

Test material

Test material information

Constituent 1

Reference substance name:

dioxo-2,4-dioxa-1,5-dialumina-3-magnesapentane oxomagnesium alumane

EC Number:

701-289-2

Molecular formula:

Al, MgO, Mg(AlO2)2

IUPAC Name:

dioxo-2,4-dioxa-1,5-dialumina-3-magnesapentane oxomagnesium alumane

Details on test material:

Content: aluminium 708,000 mg/kg, magnesium 68,000 mg/kg, ammonium 22,000 mg/kg, and other ingredients
Batch number: Delivery of 21.04.2009
Expiry date: 2011-08-21

Sampling and analysis

Analytical monitoring:

yes

Test solutions

Vehicle:

no

Test organisms

Test organisms (species):

Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)

Study design

Test type:

static

Water media type:

freshwater

Limit test:

no

Total exposure duration:

72 h

Test conditions

Nominal and measured concentrations:

nominal: 6.3, 12.5, 25, 50 and 100 mg/L

Reference substance (positive control):

not required

Results and discussion

Effect concentrations

Effect concentrations 1

Duration:

72 h

Dose descriptor:

EC50

Effect conc.:

> 100 mg/L

Nominal / measured:

nominal

Conc. based on:

other: actual loading

Basis for effect:

growth rate

Remarks on result:

other: based on Al-Skimmings

Effect concentrations 2

Duration:

72 h

Dose descriptor:

EC10

Effect conc.:

> 12.5 - < 25 mg/L

Nominal / measured:

nominal

Conc. based on:

other: actual loading

Basis for effect:

growth rate

Remarks on result:

other: based on Al-Skimmings

Effect concentrations 3

Duration:

72 h

Dose descriptor:

NOEC

Effect conc.:

12.5 mg/L

Nominal / measured:

nominal

Conc. based on:

other: actual loading

Basis for effect:

growth rate

Remarks on result:

other: based on Al-Skimmings

Effect concentrations 4

Duration:

72 h

Dose descriptor:

LOEC

Effect conc.:

25 mg/L

Nominal / measured:

nominal

Conc. based on:

other: actual loading

Basis for effect:

growth rate

Remarks on result:

other: based on Al-Skimmings

Any other information on results incl. tables

Chemical analysis

Test item concentration [mg/L]	Aluminium determination (mean of two replicates) [mg/L]
	0h	72h
Control	0.0014*	< 0.001
6.3	0.0197	0.0102
12.5	0.0190	0.0096
25	0.0270	0.0141
50	0.0824	0.0134
100	0.1062	0.0266
100 without algae	0.1279	0.0483

*The recovery of Al at a concentration slightly higher than the LOQ

(1.0 μg/L) is not considered critical with respect to control performance.

Applicant's summary and conclusion

Validity criteria fulfilled:

yes

Executive summary:

The acute toxicity of Aluminia Skimmings to alga (Desmodesmus subspicatus former name: Scenedesmus subspicatus) was tested according to OECD guideline 201 ' Alga, Growth Inhibition Test' (2006). During 72 hours exposure an ErC50 of >100 mg/L and ErC10 of >12.5<25 mg/L was measured and a NOEC of 12.5 mg/L was calculated (Currenta, 2010).