Registration Dossier
Registration Dossier
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EC number: 253-462-2 | CAS number: 37321-62-3
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Hazard for air
Hazard for terrestrial organisms
Hazard for predators
Additional information
Conclusion on classification
The hazard assessment is based on the data currently available. New studies with the registered substance and/or other member substances of the glycol esters category will be conducted in the future. The finalised studies will be included in the technical dossier as soon as they become available and the hazard assessment will be re-evaluated accordingly.
For further details, please refer to the category concept document attached to the category object (linked under IUCLID section 0.2) showing an overview of the strategy for all substances within the glycol esters category.
Classification relevant information for environmental hazard:
Biodegradation:
Based on the results of the read across substances and the QSAR predictions, the target substance dodecanoic acid, ester with 1,2-propanediol (CAS 37321 -62 -3) is considered readily biodegradable.
Aquatic acute toxicity
Aquatic invertebrates:
EL50 (48 h) = 6.59 mg/L (nominal, OECD 202)
Algae/aquatic plant:
EL50 (72 h) = 31.25 mg/L (nominal, OECD 201)
Aquatic chronic toxicity:
NOELR (72 h) = 9.76 mg/L (nominal, OECD 201)
Classification according to CLP
Based on the available data listed above, the most sensitive acute effect concentration was obtained for aquatic invertebrates, with an EL50 (48 h) of 6.59 mg/L (nominal). Thus, the substance does not need to be classified for acute aquatic toxicity according to the consolidated version of Regulation (EC) No 1272/2008 (CLP) and following amendments (ATPs).
The NOELR (72 h) = 9.76 mg/L (nominal) for algae is the only chronic aquatic effect concentration available. As the substance is readily biodegradable and the log Pow is 5.0 to >10, the substance need to be classified for chronic aquatic toxicity according to the Regulation (EC) No 1272/2008 (CLP) and following amendments (ATPs) as Aquatic Chronic 2.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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