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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Additional toxicological data

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Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
No data
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Meets generally accepted scientific standards with acceptable restrictions

Data source

Reference
Reference Type:
publication
Title:
Unnamed
Year:
2006

Materials and methods

Type of study / information:
The intraperitoneal effects of different boric acid concentrations were assessed.
Test guideline
Qualifier:
according to guideline
Guideline:
other: No data
Deviations:
not specified
Principles of method if other than guideline:
The intraperitoneal effects of different boric acid concentrations on concentrations of serum enzymes, haematological parameters and liver histology were assessed.
GLP compliance:
not specified

Test material

Constituent 1
Details on test material:
- Name of test material: Boric acid

Results and discussion

Applicant's summary and conclusion

Conclusions:
Haematological parameters slightly decreased with exposure to 750 mg/kg boric acid at 48 h but all values were not significantly different from controls. LDH and hepatocytes were unchanged. At low doses of boric acid levels of ALT, ALP and LDH as AST were unsignificantly decreased at 48 h.