Registration Dossier

Administrative data

Endpoint:
adsorption / desorption: screening
Type of information:
experimental study
Adequacy of study:
key study
Study period:
01.08.2017 - 02.11.2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))
Deviations:
not specified
Qualifier:
according to
Guideline:
EU Method C.19 (Estimation of the Adsorption Coefficient (KOC) on Soil and Sewage Sludge Using High Performance Liquid Chromatography (HPLC))
Deviations:
not specified
GLP compliance:
yes (incl. certificate)
Type of method:
HPLC estimation method
Media:
sewage sludge

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid

Study design

HPLC method

Details on study design: HPLC method:
EQUIPMENT
- Apparatus: HPLC System Agilent 1100 series
- Type, material and dimension of analytical (guard) column: commercially available cyanopropyl solid phase containing lipophilic and polar moieties, stainless steel, 5 µM

MOBILE PHASES
- Type: methanol/distilled water
- pH: 5.4

DETERMINATION OF DEAD TIME
- Method: by inert substances which are not retained by the column

REFERENCE SUBSTANCES
- Identity: Acetanilide, Atrazin, Triadimenol, Linuron, Pyrazophos, Diclofop-methyl, 4,4`-DDT

REPETITIONS
- Number of determinations: 2

EVALUATION
- Calculation of capacity factors k': according to OECD TG 121
- Determination of the log Koc value: according to OECD TG 121

Results and discussion

Adsorption coefficient
Key result
Type:
log Koc
Value:
4.3 dimensionless
pH:
5.4
Temp.:
25 °C

Results: HPLC method

Details on results (HPLC method):
- Average retention data for test substance: retention time = 1.71 (1st measurement), 1.71 (2nd measurement)

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
The log KOC of the test substance was 4.3.