Registration Dossier
Registration Dossier
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EC number: 936-617-5 | CAS number: -
Adsorption / desorption
Administrative data
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 01.08.2017 - 02.11.2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))
- Deviations:
- not specified
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.19 (Estimation of the Adsorption Coefficient (KOC) on Soil and Sewage Sludge Using High Performance Liquid Chromatography (HPLC))
- Deviations:
- not specified
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC estimation method
- Media:
- sewage sludge
Test material
- Reference substance name:
- 2-fluoro-4-(4-butylphenyl)-phenyl boronic acid
- EC Number:
- 936-617-5
- Molecular formula:
- C16 H18 B F O2
- IUPAC Name:
- 2-fluoro-4-(4-butylphenyl)-phenyl boronic acid
- Test material form:
- solid
Constituent 1
Study design
HPLC method
- Details on study design: HPLC method:
- EQUIPMENT
- Apparatus: HPLC System Agilent 1100 series
- Type, material and dimension of analytical (guard) column: commercially available cyanopropyl solid phase containing lipophilic and polar moieties, stainless steel, 5 µM
MOBILE PHASES
- Type: methanol/distilled water
- pH: 5.4
DETERMINATION OF DEAD TIME
- Method: by inert substances which are not retained by the column
REFERENCE SUBSTANCES
- Identity: Acetanilide, Atrazin, Triadimenol, Linuron, Pyrazophos, Diclofop-methyl, 4,4`-DDT
REPETITIONS
- Number of determinations: 2
EVALUATION
- Calculation of capacity factors k': according to OECD TG 121
- Determination of the log Koc value: according to OECD TG 121
Results and discussion
Adsorption coefficient
- Key result
- Type:
- log Koc
- Value:
- 4.3 dimensionless
- pH:
- 5.4
- Temp.:
- 25 °C
Results: HPLC method
- Details on results (HPLC method):
- - Average retention data for test substance: retention time = 1.71 (1st measurement), 1.71 (2nd measurement)
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- The log KOC of the test substance was 4.3.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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