Registration Dossier

Administrative data

Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
14.03.2019 - 14.03.2019
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2019
Report Date:
2019

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
EU Method A.2 (Boiling Temperature)
Qualifier:
according to
Guideline:
OECD Guideline 103 (Boiling Point)
GLP compliance:
no
Type of method:
differential scanning calorimetry
Remarks:
+ capillary method

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder

Results and discussion

Boiling point
Key result
Boiling pt.:
>= 293 - <= 298 °C
Atm. press.:
1 013 hPa
Decomposition:
yes

Any other information on results incl. tables

The test item shows an endothermic effect in the temperature range of 160 – 190 °C, which can be associated with a melting of the test item (melting point according to the certificate of analysis 171.2 – 171.7 °C). A second endothermic effect was observed in the temperature range of 250 – 310 °C, which can be assigned to a boiling of the test item accompanied by decomposition. No further thermal effects could be observed up to the maximum test temperature of 500 °C.

Table1:    Results of the DSC-measurements

No.

Sample weight / mg

Onset of Effect / °C

Range of effect / °C

Weight loss / mg

Atmospheric pressure / hPa

Remark

1

11.38

173.53
292.69

160 – 190 (endo)
250 – 310 (endo)

11.36

996.4

2

10.73

173.41
297.39

160 – 190 (endo)
250 – 310 (endo)

10.73

996.4

For the correction of the boiling temperature to normal pressure the test item was assigned to chemical group 4 (e.g. Cresols). According to appendix 8.2a correction value φ = 5.65 was used for a temperature of 300 °C.

The lowest measured onset temperature is corrected to the normal pressure to be 293.42°C and the highest onset temperature to be 298.12°C. The corrected temperatures of the boiling point differ more than 0.5 K from their mean value of 295.77°C. The test item has a boiling range under atmospheric pressure (1013 hPa) from 293 °C to 298 °C accompanied by decomposition.

Applicant's summary and conclusion

Conclusions:
Trimethylhydroquinone has a boiling point of 293-298°C at 1013 hPa accompanied by decomposition as determined by differential scanning calorimetry and capillary method.
Executive summary:

The test item Trimethylhydroquinone has a boiling point of 293-298°C at atmospheric pressure (1013 hPa) accompanied by decomposition as determined by differential scanning calorimetry and capillary method according to Regulation EC No. 440/2008 Method A.2. and OECD Test Guideline 103 (1995).