Emblic, ext.

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:

short-term toxicity to aquatic invertebrates

Remarks:

Sample sent to INTOX PVT. LTD. , 375, Urawade, Tal. Mulshi, Dist. Pune, Maharashtra, 412115, India.

Type of information:

experimental study

Adequacy of study:

key study

Study period:

34 days

Reliability:

1 (reliable without restriction)

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2018

Report date:

2018

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)

Deviations:

no

GLP compliance:

yes

Test material

Test material information

Constituent 1

Reference substance name:

Emblic, ext.

EC Number:

289-817-3

EC Name:

Emblic, ext.

Cas Number:

90028-28-7

IUPAC Name:

Beta-Glucogallin and Gallic acid are the main constituents of Emblica officinalis extract.

Test material form:

solid

Sampling and analysis

Analytical monitoring:

yes

Test solutions

Vehicle:

yes

Test organisms

Test organisms (species):

Daphnia magna

Study design

Test type:

static

Water media type:

other: reconstituted water

Limit test:

yes

Total exposure duration:

48 h

Test conditions

Hardness:

229.6 mg/L

Test temperature:

19.5°C - 20.4°C

pH:

7.85 - 8.36

Dissolved oxygen:

7.85 to 8.36 mg/L

Reference substance (positive control):

not specified

Results and discussion

Effect concentrations

Key result

Duration:

48 h

Dose descriptor:

EC50

Effect conc.:

>= 100 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mobility

Applicant's summary and conclusion

Validity criteria fulfilled:

yes

Conclusions:

The Acute immobilisation EC50 value of Emblica officinalis Extract in Daphnia magna at 48hrs exposure period is greater than 100 mg/L. The Study is performed as per OECD Guideline for testing of Chemicals, Section 2, No. 202.