Registration Dossier
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EC number: 225-533-8 | CAS number: 4904-61-4
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
No toxic effect is expected up to the limit of water solubility.
Key value for chemical safety assessment
Additional information
DuPont (2003) performed a study on the toxicity of 1,5,9-cyclododecatriene (CAS 4904-61-4) to the marine invertebrate Americamysis bahia. This study was selected as key study. The test animals were exposed under static conditions for 96 hours. The test solutions were prepared with acetone as vehicle. The test concentrations were not analytically verified. The EC50 (96 hours) was calculated to be 0.47 mg/L (nominal) indicating that the test substance may be very toxic to aquatic invertebrates. However, the effect value is above the limit of water solubility (0.28 mg/L at 20 °C; AQura, 2010). Therefore, no toxic effect is expected up to the limit of water solubility.
The toxicity of 1,5,9-cyclododecatriene (CAS 4904-61-4) to the freshwater invertebrate Daphnia magna was tested in a static test according to the German Industrial Standard DIN 38412, part 11 (Hüls, 1988; report no. D 372). The exposure duration was only 24 hours. The test concentrations were not analytically verified. The 24-h EC50 (immobilization) was determined to be 2.9 mg/L (nominal). Solvent was not used to prepare the test solutions. As the effect value is above the limit of water solubility (0.28 mg/L at 20 °C; AQura, 2010), no toxic effect is expected up to the limit of water solubility.
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