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EC number: 917-865-3
CAS number: -
objective of the present study was to identify potential toxic effects
of the test item after single oral administration to rats in a stepwise
The study was started with
2000 mg/kg bw in 3 female rats and continued with further 3 females
treated with 2000 mg/kg bw.
and clinical signs were monitored for at least 6 hours after
administration and then daily. All animals were weighed before treatment
(day 1) and on days 2, 4, 6, 8, 11, 13, and 15. At the end of the
observation period, all surviving rats were sacrificed and subjected to
a detailed necropsy.
No mortality occurred during
the course of this study.
No clinical signs of
toxicity were observed.
The body weight development
was inconspicuous throughout the study.
The gross pathological
examination revealed no organ alterations.
test item has no acute toxic potential under the conditions of the
present study, and the LD50 value is higher than 2000 mg/kg
after single oral administration in female rats.
This study was performed according
to GLP and is fully compliant with OECD TG 423. The test item has
no acute toxic potential under the conditions of the present study, and
the LD50value is higher than 2000 mg/kg after single oral
administration in female rats.
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