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EC number: 701-290-8 | CAS number: -
The acute dermal toxicity of sucrose diacetate hexaisobutyrate (SAIB) was evaluated in Sprague Dawley rats. A limit dose of 20 mL/kg was applied to the skin after the hair was removed from the skin with an electric clipper. An occlusive wrap was used to hold the test material against the skin for 24 hours, and at the end of exposure, residual test material was washed off with running water. No abnormal clinical signs or signs of irritation at the site of application of the test material were observed during the 14-day observation period. All animals gained weight normally, and based on weight gain and survival rate, no signs of percutaneous absorption were evident. The acute dermal LD50 for SAIB was determined to be > 20000 mg/kg.
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