Registration Dossier

Physical & Chemical properties

Partition coefficient

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
21st March to 12th April, 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
other: EU Method A.24: Partition Coefficient (n-octanol/water), High Performance Liquid Chromatography (HPLC) Method.
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Qualifier:
according to
Guideline:
EPA OPPTS 830.7570 (Partition Coefficient, n-octanol / H2O, Estimation by Liquid Chromatography)
GLP compliance:
no
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Specific details on test material used for the study:
SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: 171116
- Expiration date of the lot/batch: 16th November, 2019
- Purity test date: 16th November, 2017
- Purity: 99.5%
- Appearance: White to pale yellow/green powder

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: At room temperature protected from light
Analytical method:
high-performance liquid chromatography
Key result
Type:
log Pow
Partition coefficient:
5.2
Temp.:
35 °C
pH:
7
Type:
Pow
Partition coefficient:
170 000
Temp.:
35 °C
pH:
7
Conclusions:
The log Pow of the substance is 5.2 at 35 °C.
Executive summary:

The partition coefficient of the test substance has been determined by the HPLC method according to EC test guideline A.24, OECD test guideline 117, and OPPTS test guideline 830.7570. The log Pow of the substance has been determined to be 5.2 in a column at 35°C.

Description of key information

The partition coefficient of the test substance has been determined by the HPLC method according to EC test guideline A.24, OECD test guideline 117, and OPPTS test guideline 830.7570. The log Pow of the substance has been determined to be 5.2 in a column at 35 °C.

Key value for chemical safety assessment

Log Kow (Log Pow):
5.2
at the temperature of:
35 °C

Additional information