Registration Dossier

Physical & Chemical properties

Particle size distribution (Granulometry)

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
ISO 13320 (Particle size analysis - Laser diffraction methods)
Qualifier:
according to
Guideline:
other: CIPAC MT 187 “Particle Size Analysis by Laser Diffraction”
GLP compliance:
yes (incl. certificate)
Type of method:
Laser scattering/diffraction
Mass median aerodynamic diameter:
51.6 µm
Geometric standard deviation:
0.267
Key result
Percentile:
D90
Mean:
115 µm
St. dev.:
1.4
Key result
Percentile:
D50
Mean:
49 µm
St. dev.:
0.283
Key result
Percentile:
D10
Mean:
13.5 µm
St. dev.:
0.091
Conclusions:
The MMAD was determined to be 51.6 µm. The volume of sample with a particle size of less than 10.00 μm was 5.81%.
Executive summary:

The particle size of the substance was determined by a laser diffraction test, using the dry powder module (DPM). The MMAD was determined to be 51.6 µm. The volume of sample with a particle size of less than 10.00 μm was 5.81%.

Description of key information

The particle size of the substance was determined by a laser diffraction test, using the dry powder module (DPM). The MMAD was determined to be 51.6 µm. The volume of sample with a particle size of less than 10.00 μm was 5.81%.

Additional information